8 results
Lesions of the Spinal cord - Spinal Cord Syndromes

Spinal cord lesions can result in permanent neurologic
Syndromes Spinal ... Causes of spinal ... syphilis, and HIV ... anesthesia (more commonly ... anesthesia (more commonly
Alexia Without Agraphia
Alexia without agraphia is a disconnection syndrome where patients cannot read but can write.
disconnection syndrome ... occlusion is the most common ... cause, leading ... Pathophysiology: ... Infarct (most common
Spinal Cord Disorders - Differential Diagnosis Framework

Spinal cord neurological lesion:
Clinical findings:
 • Symptoms and signs below
often- Sensory ataxia ... Cord Causes: 1 ... , HIV, CMV, HTLV ... MCTD, Sjogren syndrome ... differential #algorithm
HIV-Associated Neurocognitive Disorder (HAND)

Definition:
HIV-Associated Neurocognitive disorders categories:
• Asymptomatic neurocognitive impairment
• Mild neurocognitive impairment
• HIV dementia

Pathophysiology:
HIV frequently
dementia Pathophysiology ... barrier (BBB), and infects ... volume • Patchy areas ... of high signal ... The clinical syndrome
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
Affects 1:25,000 ... - gastric and breast ... DDX - Other causes ... : • Nephrotic syndrome ... , HIV) • Glucocorticoid
Guillain-Barré Syndrome (GBS)
Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness
Epidemiology:
 • Incidence: 1
Guillain-Barré Syndrome ... Common organisms ... : • Most common ... immunodeficiency virus (HIV ... the underlying pathophysiology
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Epidemiology: • 1-2 cases ... Guillain-Barre Pathophysiology ... Campylobacter jejuni - HIV ... Opthaloplegia • Ataxia ... of intrathecal spinal
Stiff Person Syndrome (SPS) - Diagnosis and Management Summary

Epidemiology:
 • Prevalence: 1-2 cases per million -
Prevalence: 1-2 cases ... times than men • Commonly ... and pernicious anemia ... Pathophysiology ... the brain and spinal