9 results
Lesions of the Spinal cord - Spinal Cord Syndromes

Spinal cord lesions can result in permanent neurologic
Syndromes Spinal ... HIV) - Vitamin ... - Friedreich ataxia ... anesthesia (more commonly ... anesthesia (more commonly
Alexia Without Agraphia
Alexia without agraphia is a disconnection syndrome where patients cannot read but can write.
disconnection syndrome ... occlusion is the most common ... Pathophysiology: ... Infarct (most common ... #diagnosis #pathophysiology
HIV-Associated Neurocognitive Disorder (HAND)

Definition:
HIV-Associated Neurocognitive disorders categories:
• Asymptomatic neurocognitive impairment
• Mild neurocognitive impairment
• HIV dementia

Pathophysiology:
HIV frequently
dementia Pathophysiology ... infects the CNS ... of high signal ... The clinical syndrome ... ataxia
Spinal Cord Disorders - Differential Diagnosis Framework

Spinal cord neurological lesion:
Clinical findings:
 • Symptoms and signs below
often- Sensory ataxia ... , HIV, CMV, HTLV ... MCTD, Sjogren syndrome ... disorders #diagnosis #neurology ... differential #algorithm
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
Affects 1:25,000 ... - gastric and breast ... : • Nephrotic syndrome ... (Epstein-Barr syndrome ... , HIV) • Glucocorticoid
Guillain-Barré Syndrome (GBS)
Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness
Epidemiology:
 • Incidence: 1
Guillain-Barré Syndrome ... Common organisms ... : • Most common ... immunodeficiency virus (HIV ... the underlying pathophysiology
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Guillain-Barre Pathophysiology ... Campylobacter jejuni - HIV ... Paresthesias: Hands ... Opthaloplegia • Ataxia ... of intrathecal spinal
Stiff Person Syndrome (SPS) - Diagnosis and Management Summary

Epidemiology:
 • Prevalence: 1-2 cases per million -
times than men • Commonly ... pernicious anemia ... Pathophysiology ... spinal cord. ... Management #treatment #neurology
Multiple Sclerosis - Summary

Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
• Or brainstem syndromes ... Afferent pupillary defect ... Cramping, Weakness, Ataxia ... Progressive MS (Spinal ... • Acute: - IV