14 results
Characteristic clinical manifestations of Down syndrome 
 
Typical craniofacial appearance 
 • Round face and flat
manifestations of Down syndrome ... folds (a fold of skin ... Single palmar creases ... #Downs #Syndrome ... #PhysicalExam #
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
bone, joint, and skin ... • Pustular skin ... dermatoses • Skin ... the collar bone, breast ... Rheumatology #diagnosis #management
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS)
Definition: 
 • Severe adverse drug reaction, characterized by
characterized by extensive skin ... least 2 different areas ... Skin involvement ... Exanthematous Pustulosis Management ... SinaiBmoreIMRes #DRESS #Syndrome
Acromegaly - Diagnosis and Management Summary - GrepMed Handbook 

Clinical Presentation: 
 • Classic Acromegaly: frontal
Diagnosis and Management ... , hair growth, skin ... tags, skin thickening ... Mortality due to CVD ... Beckwith Wiedemann syndrome
Pruritus Treatment Algorithm for Hemodialysis Patients 

Non-PharmacoIogicaI Measures 
 • Use gentle soap e.g. Dove
except if other areas ... trimmed • For dry skin ... Uremic #Uremia #Management ... #Nephrology #CKD
Penicillin Allergy Pathway for Antibiotic Prescription in Patients With Penicillin Allergy
Mild Reaction - Itching, Minor rash
mucosal involvement, skin ... Stevens-Johnson syndrome ... systemic symptoms syndrome ... cephalosporin, please ... Prescription #algorithm #management
Hamartomatous Polyposis Syndromes - Peutz-Jeghers Syndrome (PJS), Juvenile Polyposis Syndrome (JPS), Cowden Syndrome (CS), Cronkhite-Canada (CC),
Peutz-Jeghers Syndrome ... (JPS), Cowden Syndrome ... Cancer + Uterine, Breast ... Trichilemmomas (bumpy skin ... #diagnosis #management
Statin Induced Muscle Toxicity - Summary

Clinical Presentation:
 • Elevations of serum creatine kinase with proximal myalgia
weakness without skin ... Guillain-Barré syndrome ... antisynthetase syndrome ... Diagnosis: • CK ... myopathy #diagnosis #management
Gout - Diagnosis and Management Summary

3 Conditions for Gout to Manifest:
1. Hyperuricemia
2. Monosodium urate deposition in
Diagnosis and Management ... sex • Metabolic syndrome ... Decrease dosage in CKD ... attack + stage ≥3 CKD ... Gout #diagnosis #management
Staphylococcal Scalded Skin Syndrome (SSSS) 
(aka Ritter disease) 
Nikolsky positive 
Clinical 
• Typically occurs 3 to
Staphylococcal Scalded Skin ... Syndrome (SSSS) ... Conjunctivitis Management ... Staphylococcal #Scalded #Skin ... #Syndrome #SSSS