3 results
Pathophysiology of Tumor Lysis Syndrome (TLS)
Tumor Cell Lysis
-> Release of DNA
 • Purines -> Hypoxanthine /
Pathophysiology ... Lysis Syndrome (TLS ... ) Tumor Cell Lysis ... Precipitation => • Urate ... Hypocalcemia • Hyperkalemia
Summary of Oncologic Emergencies

Neutropenic fever:
- Fever + ANC < 500 → start cefepime ± vancomycin (if
suspected) - CT ... chest; CT abdomen ... antibiotics TLS ... interventional radiology ... plasmapheresis Hypercalcemia
Squamous-Cell Carcinoma of the Lung- ...Physical examination revealed decreased air entry in the base of the
Squamous-Cell Carcinoma ... that were in his breast ... #NEJM #clinical ... #radiology #CT # ... squamous #cell #