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Diffuse large B cell lymphoma (DLBCL) - Management and Treatment Algorithm

By Matthew Ho, MD PhD @MatthewHoMD

#Diffuse
Diffuse large B cell ... Management and Treatment ... Algorithm By ... Diffuse #large #Bcell ... #Algorithm #oncology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
is of B-cell lineage ... marrow • Mature B-cell ... involvement • T-cell ... Intracellular Urate ... Leukemia #Hematology #Oncology
Blood Disorders - Markers and Differential Diagnosis Algorithm 
Acute
 • Myloid (AML) - CD13, CD33, CD34,
Diagnosis Algorithm ... CD10 - T-cell ... - CD7, CD3 Chronic ... • Lymphoid (CLL ... Cells - B-cell
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Chronic Lymphocytic ... and other C Cell ... microglobulin Treatment ... #Chronic #Lymphocytic ... diagnosis #workup #oncology
Chronic Neutrophilic Leukemia (CNL)

 • Signaling Pathway
 • WHO Dx Critera
 • Risk Stratification
 • Treatment
Chronic Neutrophilic ... Stratification • Treatment ... Algorithm Zhuoer ... #Chronic #Neutrophilic ... Leukemia #diagnosis #oncology
Causes of Ovarian Mass - Differential Diagnosis Algorithm
Hyperplastic:
 • Polycystic ovary
 • Endometrioid cyst
Functional:
 • Follicular
Ovarian Mass - Differential ... Diagnosis Algorithm ... • Granulosa cell ... • Granulosa cell ... metastasis) • Breast
High Attenuation pattern 
1. Chronic eosinophilic pneumonia with peripheral areas of ground glass opacity.
2. Sarcoid end-stage
Chronic eosinophilic ... with peripheral areas ... Chronic eosinophilic ... Broncho-alveolar cell ... HighAttenuation #Pattern #Comparison
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison

Hodgkin's Lymphoma:
 • Epidemiology: young adults 20-30, older 50-70
 •
typically of B-cell ... Reed Sternberg cell ... based on: - Cell ... type (B cell, T ... #oncology #diagnosis
Primary Bone Tumors - Differential Diagnosis Algorithm 

Metastatic - Most common tumour in adults
 - Breast
Bone Tumors - Differential ... Diagnosis Algorithm ... in adults - Breast ... Non-Malignant • Giant Cell ... Orthopedics #Causes #Oncology
Eosinophilia - Differential Diagnosis Algorithm
Idiopathic Eosinophilia
Primary Eosinophilia:
 • Primary hypereosinophilic syndrome
 • Eosinophilic Leukemia
 • MPN/MDS
Diagnosis Algorithm ... , T-cell leuk/lymphoma ... , B-cell lymphomas ... mastocytosis, Langerhans cell ... insufficiency, Chronic