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diagnosis algorithm differential cholangitis cirrhosis hemophagocytic hlh lymphohistiocytosis pbc ascites hivaids infections opportunistic pharmacology prevention rheumatology summary workup acute alkaline
Causes of Severe Acute Liver Injury - Ichemic hepatitis - Acute biliary obstruction - Drug-Induced liver
Causes of Severe ... hepatitis - Acute biliary ... Hemochromatosis - Primary ... biliary cholangitis ... #Differential #Hepatology
Hepatomegaly - Differential Diagnosis Algorithm Malignant • Primary Carcinoma • Metastases • Lymphoma • Leukemia • Polycythemia
Malignant • Primary ... Histiocytosis X • Primary ... Cholangitis • Primary ... Biliary Cirrhosis ... #Hepatology
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Causes of Thrombocytosis ... Myelogenous Leukemia • Primary ... effect following treatment ... Diagnosis #Algorithm #Causes ... #Hematology
Jaundice - Differential Diagnosis Algorithm Pre-Hepatic - Unconjugated Hyperbilirubinemia Increased Production • Hemolysis • Ineffective Erythropoiesis • Hematoma Decreased
on Ultrasound Biliary ... Gallstones • Biliary ... Cholangiocarcinoma • Primary ... Diagnosis #Algorithm #Causes ... #Hepatology #bilirubinemia
Common Etiologies of Cirrhosis Inflammation - Hepatitis B (15 percent) - Hepatitis C (47 percent) - Schistosomiasis
congenital - Primary ... biliary cirrhosis ... #Differential #Hepatology ... #Cirrhosis #Causes
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 Causes of Ascites - Differential Diagnosis Algorithm Portal Hypertension - Prehepatic: • Portal vein thrombosis • Splenic
Causes of Ascites ... liver failure • Primary ... biliary cholangitis ... • Primary sclerosing ... Diagnosis #Algorithm #Hepatology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
non-essential drug/HDS treatments ... for alternative causes ... obstruction, Primary ... , Primary sclerosing ... Diagnosis #Algorithm #hepatology
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm ALP: - Enzymes that catalyze hydrolysis of organic phosphate
Intestine - Other causes ... - Drugs - Primary ... biliary Cholangitis ... PSC - Other biliary ... Diagnosis #Algorithm #hepatology
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
Primary Biliary ... intralobular bile ducts causes ... Drug-induced cholestasis, Primary ... malignancy #Primary ... diagnosis #workup #hepatology
Portal Hypertension - Differential Diagnosis Portal Pressure = the pressure difference between the pressure in the portal
Post-Hepatic: • Cardiac causes ... pregnancy • Primary ... biliary cirrhosis ... Differential #Diagnosis #causes ... #hepatology
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