23 results
diagnosis differential algorithm management anemia rheumatology dermatology hemeonc hemolysis hemolytic hemophagocytic hlh intravascular leukemia lymphohistiocytosis allergy chronic classification cll coagulation
Hemolysis - Diagnostic Algorithm and Causes Increased red cell production: • Increased Reticulocytosis/polychromasia • Erythroid
Algorithm and Causes ... Increased red cell ... Increased red cell ... Urobilinogen • + urinary ... #Workup #Hematology
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Causes of Thrombocytosis ... Myelogenous Leukemia • Primary ... • Rheumatic disorders ... effect following treatment ... #Hematology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
/Quantity: • Primary ... marrow disease - DIC ... Coagulation Defects: • DIC ... Purpura Fulminans (DIC ... Differential #Diagnosis #hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
and Platelet Disorders ... Diagnosis and Workup ... unclear, or if a primary ... hematologic disorder ... #Workup #hematology
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Eosinophil Disorders ... evaluation or workup ... /µL Workup • Screen ... glucocorticoid treatment ... Differential #diagnosis #hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... intravascular coagulation (DIC ... usually IgM) (e.g. primary ... lymphoproliferative disorders ... differential #diagnosis #hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
lymphoproliferative disorders ... microglobulin Treatment ... lymphoma • Hairy cell ... Leukemia #diagnosis #workup ... #oncology #hematology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
Schistocytes, helmet cells ... : • Treat primary ... cause • Correct ... #treatment #management ... #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
-> AML: Blast crises ... + distinctive primary ... Fibrinolysis & DIC ... #Leukemia #Hematology ... #Oncology #Diagnosis
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
for alternative causes ... biliary obstruction, Primary ... biliary cholangitis, Primary ... Hepatic vascular disorder ... Diagnosis #Algorithm #hepatology
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