15 results
Pathophysiology of Tumor Lysis Syndrome (TLS)
Tumor Cell Lysis
-> Release of DNA
 • Purines -> Hypoxanthine /
Pathophysiology ... of Tumor Lysis Syndrome ... (TLS) Tumor Cell ... #TLS #Pathophysiology ... #UricAcid
Causes of Pediatric Diarrhea - Differential Diagnosis Algorithm
Infectious:
 • Viral
 • Bacterial
 • Parasitic
Malabsorption:
 • Lactase
Causes of Pediatric ... Toddler's Diarrhea • Constipation ... • Short Bowel Syndrome ... Irritable Bowel Syndrome ... #Peds #Pediatrics
Causes of Pediatric Constipation - Differential Diagnosis Algorithm
Dietary / Functional:
 • Insufficient Volume / Bulk
Neurologic:
 •
Causes of Pediatric ... Constipation - ... Guillain-Barré Syndrome ... Diagnosis #Algorithm #Causes ... #Peds #Pediatrics
Serotonin-Norepinephrine Reuptake Inhibitors(SNRIs): Mechanisms and Side Effects

Withdrawal: Dizziness, Diarrhea, Insomnia, Nausea, Vomiting
Serotonin Syndrome - Potentially Life
Diarrhea, Insomnia, Nausea ... Vomiting Serotonin Syndrome ... gain Incr NE: Nausea ... , Diaphoresis, Constipation ... SerotoninNorepinephrine #Inhibitors #Pathophysiology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... high WBC count cause ... leukapheresis - TLS ... : • Pathophysiology ... #TLS #diagnosis
Causes of Neuromuscular Weakness
 • Spinal Cord: Demyelinating Disease (MS), Epidural abscess, Infarction, Syringomyelia, Tetanus, Transverse
Causes of Neuromuscular ... Motor Nerves: ALS ... Guillain-Barre syndrome ... Lambert Eaton Syndrome ... Shellfish poisoning, Meds
Schematic representation of the major sources of ammonia production and its excretory pathway (GI = gastrointestinal,
although hepatic causes ... namely, the many causes ... rare): - Reye syndrome ... (Peds) - Primary ... deficiency #Ammonia #Pathophysiology
Anticonvulsants as Mood Stabilizers: Mechanism and Side-effect
Examples: Valproate, Carbamazepine, Lamotrigine
 • Mild anticholinergic effect -> Drowsiness
blurred vision constipation ... Stevens-Johnson Syndrome ... Systemic effect -> Nausea ... #SideEffects #Pathophysiology
Type IV Hypersensitivity: Pathogenesis and clinical findings
Definition: Unique because it is entirely T-Cell mediated; exposure to
exposure to allergen causes ... mast cells or CTLs ... Stevens-Johnson Syndrome ... Allergy #Immunology #pathophysiology
Rhabdomyolysis - Differential Diagnosis and Management Summary

Trauma:
 • Immobilization, Crush iniury, Compartment syndrome, Electrical injury
Exertional:
 •
iniury, Compartment syndrome ... Neuroleptic malignant syndrome ... HIV, Influenza, TSS ... Dermatomyositis) AKI - Pathophysiology ... Management #Summary #causes