42 results
Pathophysiology of Tumor Lysis Syndrome (TLS)
Tumor Cell Lysis
-> Release of DNA
 • Purines -> Hypoxanthine /
of Tumor Lysis Syndrome ... (TLS) Tumor Cell ... #TumorLysis #Syndrome ... #TLS #Pathophysiology ... #UricAcid
Reflex Testing - Causes of Hyporeflexia and Hyperreflexia
Focal Hyporeflexia: 
 • Radiculopathy, Mononeuropathy, Polyneuropathy, Acute stroke,
Reflex Testing - Causes ... Deep coma (any cause ... Guillain-Barré syndrome ... injury, Early ALS ... Hyperthyroidism, Serotonin syndrome
Tumor Lysis Syndrome
An acute, life-threatening condition that appears within 7 days of starting cytotoxic therapies in
Tumor Lysis Syndrome ... #Tumor #Lysis #Syndrome ... #TLS #oncology ... #management #UricAcid
Marcus Gunn Phenomenon - Jaw Winking Syndrome

Jaw-winking syndrome is thought to be caused by abnormal innervation
- Jaw Winking Syndrome ... Jaw-winking syndrome ... thought to be caused ... Most cases are congenital ... #clinical #video
Pemberton's Sign caused by a Retrosternal Thyroid Goiter

Elevating the arms causes the previously flat neck veins
Pemberton's Sign caused ... Elevating the arms causes ... superior vena cava syndrome ... PhysicalExam #clinical #video ... neck #mass #SVC #Syndrome
Dyspnea - Differential Diagnosis Framework

Cardiovascular Causes of Dyspnea:
 • Myocardium:
	- Heart failure
	- CAD/ACS
	- Valvulopathy
 • Electrical:
	-
Cardiovascular Causes ... Tamponade Pulmonary Causes ... Hepatopulmonary syndrome ... Other Causes ... Guillain Barre - ALS
Causes of Hyperuricemia
Increased production
 • Solid-organ transplant
 • Tumor lysis syndrome
 • Rhabdomyolysis
 • Lesch Nyhan
Causes of Hyperuricemia ... • Tumor lysis syndrome ... • Lesch Nyhan syndrome ... Hyperuricemia #Causes ... #UricAcid #diagnosis
Causes of Neuromuscular Weakness
 • Spinal Cord: Demyelinating Disease (MS), Epidural abscess, Infarction, Syringomyelia, Tetanus, Transverse
Causes of Neuromuscular ... Motor Nerves: ALS ... Guillain-Barre syndrome ... Lambert Eaton Syndrome ... Neuromuscular #Weakness #Causes
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
vs Tumor Lysis Syndrome ... high WBC count cause ... hyperviscosity syndrome ... leukapheresis - TLS ... #TLS #diagnosis
Horner's Syndrome on Physical Exam

A 75yoF was referred in for facial swelling and eyelid changes 1
Horner's Syndrome ... diagnosis of Horner's syndrome ... experience, the cause ... The video highlights ... #clinical #video