12 results
Tumor Lysis Syndrome - Workup and Management

Initial workup: BMP, Serum uric acid, LDH, Urine output, Consider
Tumor Lysis Syndrome ... - Workup and Management ... uric acid, LDH, Urine ... ≥ 8 mg/dL • Potassium ... of the above Treatment
Hypokalemia Evaluation Algorithm

Before evaluating hypokalemia, life threatening complications such as arrhythmias and paralysis should be looked
Hypokalemia Evaluation Algorithm ... treated with IV potassium ... A urine K/Cr ratio ... • Diarrhea A urine ... #nephrology #low
Classification of Tumor Lysis Syndrome (TLS) and Treatment of Metabolic Abnormalities of TLS
Laboratory TLS:
 • Uric
Classification of Tumor Lysis ... Syndrome (TLS) ... Metabolic Abnormalities ... 8.0 mg/dL • Potassium ... TLS #diagnosis #management
Metabolic Alkalosis - Urinary Chloride Algorithm
Cl- responsive metabolic alkalosis
 • Kidney loss of Cl-
Urinary Chloride Algorithm ... diuretic use, Bartter syndrome ... , Gitelman syndrome ... of sodium and potassium ... #Algorithm #nephrology
Rhabdomyolysis - Differential Diagnosis and Management Summary

Trauma:
 • Immobilization, Crush iniury, Compartment syndrome, Electrical injury
Exertional:
 •
Diagnosis and Management ... iniury, Compartment syndrome ... , Heat stroke, Metabolic ... hour with goal urine ... Monitor potassium
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
Framework and Management ... Heat stroke - Metabolic ... Weakness - Dark urine ... Monitor potassium ... #nephrology
Hyperkalemia - Diagnosis and Management - GrepMed Handbook

S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
Acidosis, Cell Lysis ... reabsorption) Workup ... ) ± Urine ... #Treatment #potassium ... #nephrology #K
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
Hypochloremic metabolic ... Hypocalciuria (spot urine ... Rhabdomyolysis Treatment ... #diagnosis #nephrology ... #management #pathophysiology
Methotrexate Renal Toxicity 
Prevention:
 • Alkalinize the urine, keep urine ph >7
 • Start pre-treatment 12
, keep urine ph ... fluids till you see metabolic ... alkalosis • Forced ... Renal #Toxicity #management ... #treatment #nephrology
Hyponatremia - Diagnosis and Treatment
Hyponatremia is usually caused by the inability to excrete water normally.
3 questions to work ... Measure urine osmolality ... Treatment: Treatment ... demyelination syndrome ... #management #nephrology