11 results
Glomerular Diseases - Nephritic and Nephrotic Syndromes

Nephritic syndrome—due to GBM disruption. 
Hypertension. t BUN and creatinine.
to GBM disruption ... RBC casts in urine ... but in severe cases ... May be 10 (eg direct ... #Proteinuria #Nephrology
Urine Microscopy - Casts
Acellular Casts
 • Hyaline Casts - Consists of only precipitated Tamm-Horsfell protein without
Urine Microscopy ... suggestive of nephrotic sydnrome ... colored compounds (e.g ... #Urine #Microscopy ... #nephrology #interpretation
Causes of Proteinuria - Differential Diagnosis Algorithm
Persistent Proteinuria >150mg/d protein present on repeat testing including overnight
Causes of Proteinuria ... • Fanconi's syndrome ... sediment - WBC/RBC casts ... Protein deposition (eg ... #Proteinuria #Nephrology
BEE Syndromes - Non-inflammatory Causes

Immune-mediated conditions affecting the Brain, Eye, and Ear

Visual or auditory symptoms in
BEE Syndromes - ... Non-inflammatory Causes ... affecting the Brain ... neuropathy (LHON) plus MRI ... #Syndromes #neurology
Guillain-Barré Syndrome (GBS)
Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness
Epidemiology:
 • Incidence: 1
Guillain-Barré Syndrome ... Incidence: 1 to 2 cases ... Immune response can be ... - Spinal MRI may ... Guillain #Barre #Syndrome
CNS Ring-Enhancing Lesions - Immunocompromised vs Immunocompetent
Multiple Ring-Enhancing Lesions:
 • Toxoplasmosis (CD4 < 100)
 • Other
Diagnosis- Compatible syndrome ... + MRI lesions + ... RingEnhancing #Lesions #Brain ... differential #diagnosis #causes ... #radiology #neurology
Algorithm - Approach to the differential diagnosis of the patient presenting with overt glomerular proteinuria. CMV
Cytomegalovirus; GBM ... hemolytic-uremic syndrome ... arbitrarily defined as urine ... cell/white cell casts ... #nephrology
Pulmonary Renal Syndromes - OnePager Summary
Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
EGPA) • Renal: (AKI ... antibody • Urine ... : UA, Urine protein ... Goodpasture's cause ... hematuria, RBC casts
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
Myotonic dystrophy - Brain ... PCB variants of GBS ... Serologic and EMG ... failure - Can be ... diagnosis #management #neurology
Orbital Apex Syndrome secondary to Herpes Zoster Ophthalmicus (HZO)

This 81 yo male was referred to our
other potential causes ... The MRI findings ... acyclovir 10mg/kg ... condition can be ... steroids (some cases