13 results
Metformin Pharmacology Summary
Mechanisms of Action:
 • Suppresses gluconeogenesis by the liver
 • Increases insulin-mediated glucose utilization
Metformin Pharmacology ... agent • Does not cause ... about causing lactic ... #Summary #DM2 # ... diabetes #endocrinology
SGLT2 Inhibitors 
SGLT2 inhibitors are the newest class of anti-diabetic medications, with the first one (Canagliflozin)
class of anti-diabetic ... kidney), which causes ... glucose in the urine ... SGLT2 #Inhibitors #Pharmacology ... #Medications #DM2
How Do I Approach the Patient with High Lactate? - Differential Diagnosis for Lactic Acidosis

#Lactic #LacticAcidosis
- Differential Diagnosis ... for Lactic Acidosis ... #Differential #Table ... #Diagnosis #CriticalCare ... #Causes
Diabetes Mellitus Type 2 Inpatient Medication Guide

Classes: Biguanide, Sulfonylurea, TZD, DPP-4 inhibitor, GLP-1 receptor agonist, SGLT2i,
Diabetes Mellitus ... Medication Guide Classes ... #Mellitus #DM2 ... #Medications #pharmacology ... #comparison #table
DPP-4 Inhibitors - Pharmacology Summary
Mechanisms of Action: Inhibits DPP-4 (dipeptidyl peptidase 4), which normally inactivates GLP-1
4 Inhibitors - Pharmacology ... not definitively cause ... DPP4 #Inhibitors #Pharmacology ... #Summary #DM2 # ... diabetes #endocrinology
Lactic Acidosis - Differential Diagnosis Framework

Type A: Impaired O2 Delivery (DO2)
 • Decreased O2 Delivery: Hypotension
Lactic Acidosis ... - Differential Diagnosis ... Impaired O2 Delivery (DO2 ... Leukemia/Lymphoma), Diabetes ... #criticalcare #
GLP-1 Receptor Agonists - Pharmacology Summary
Mechanisms of Action: Stimulate glucose-dependent insulin release from the pancreas (GLP-1
Receptor Agonists - Pharmacology ... Ozempic), or daily tablet ... not definitively cause ... #Summary #DM2 # ... diabetes #endocrinology
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis

The most common causes of hyperlactatemia are usually:
- Differential Diagnosis ... excretion (e.g., urine ... laboratory or diagnostic ... • Type B1: - Diabetes ... #Differential #Diagnosis
Metabolic Alkalosis - Urinary Chloride Algorithm
Cl- responsive metabolic alkalosis
 • Kidney loss of Cl-
metabolic acidosis • Diabetic ... ketoacidosis • D-lactic ... Urine chloride is ... the indicated causes ... #differential #diagnosis
Pain, Agitation, and Delirium (PAD) in the ICU
Addressing the ICU Triad (PAD) can be accomplished through
can result in lactic ... No pharmacologic ... (Haldol) - No pharmacologic ... Delirium #PAD #ICU #CriticalCare ... #diagnosis #management