12 results
Metformin Associated Lactic Acidosis (MALA) 

Pathophysiology of MALA
 - Metformin interferes with the activity of the
cycle found in the liver ... Diagnosis of MALA ... gastrointestinal distress and acute ... kidney injury are ... also includes symptoms
Clinical manifestations of acute liver failure 

Brain: 
Hepatic encephalopathy,  
Cerebral edema,  
Intracranial hypertension,
Seizures Kidney ... : Loss of metabolic ... lung injury, ... #Signs #Symptoms ... #Diagnosis
Acute Kidney Injury - Classification
Prerenal:
 • Dehydration
 • Heart failure (a.k.a. cardiorenal syndrome)
 • Liver failure
Acute Kidney Injury ... cardiorenal syndrome) • Liver ... #Kidney #Injury ... Classification #diagnosis ... #nephrology
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Acute Liver Injury ... - Differential ... Diagnosis Algorithm ... Liver Injury: ... • Metabolic/Hereditary
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis
Baseline Investigations: full blood count with differential,
Acute Kidney Injury ... Diagnosis Baseline ... cardiac imaging #Acute ... #Kidney #Injury ... #Diagnosis #nephrology
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
Diagnosis Framework ... Heat stroke - Metabolic ... nephrotoxicity to kidney ... Isotonic fluid/Lactated ... causes #treatment #nephrology
Guide to Acute Kidney Injury (AKI)

What to ask/look for: 
 - HPI, PMH, full ROS
Guide to Acute Kidney ... Injury (AKI) ... - TTE/liver fxn? ... UOP/weights - Urine ... #Diagnosis #Algorithm
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis

The most common causes of hyperlactatemia are usually:
Lactic Acidosis - Differential ... excretion (e.g., urine ... sweat) - its metabolism ... or renal injury ... Injury: • Reduced
Elevated Lactate Dehydrogenase (LDH) - Differential Diagnosis Framework

LDH is a cytoplasmic enzyme present in tissues throughout
Elevated Lactate ... Diagnosis Framework ... RBCs, muscle, liver ... , and kidney • ... associated with any symptoms
Heat Illnesses and Heat Stroke - Differential Diagnosis Framework

Heat Cramps:
 • Muscle pain or spasm -
Heat Stroke - Differential ... Diagnosis Framework ... involvement: Muscles, Kidneys ... : - Metabolic ... Syncope • Signs/Symptoms