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hematology chronic differential hemeonc lymphocytic agglutinin algorithm anemia cancer emergencies erythematosus hemolytic hodgkins lupus lymphoma management mds monoclonal myelodysplasia myelodysplastic
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
APML, CLL Acute ... extramedullary disease ... ) CLL Symptoms: ... #Hematology #Oncology ... #Diagnosis
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
with no early symptoms ... Diagnosis: • ... cells can indicate disease ... leukemia #CLL ... #oncology #hematology
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
Non-Hodgkin's Lymphoma - Comparison ... involved) • No leukemic ... Differential Diagnosis ... #NonHodgkins #comparison ... #oncology #diagnosis
Cold Urticaria Prevalence - 0.05% in the population Disease onset - Mostly 2nd to 4th decades of life Causes
and duration of symptoms ... angioedema Other symptoms ... Disorientation, vertigo Diagnostic ... #diagnosis #rheumatology ... #comparison #table
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
lymphoid malignancy (CLL ... significance (MGUS), CLL ... passage of red-brown urine ... hemolytic #anemia #hematology ... #diagnosis
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
minimal tumor burden Diagnosis ... chemotherapy for low-risk disease ... uw_IMresidency #CLL ... #oncology #hematology ... #hemeonc #diagnosis
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
Lymphoma (HCV) • CLL ... • Heavy Chain disease ... anemia due to cold ... #Differential #Diagnosis ... #Oncology
Summary of Oncologic Emergencies Neutropenic fever: - Fever + ANC < 500 → start cefepime ± vancomycin (if
Summary of Oncologic ... replacement Cord ... Usually myeloid leukemias ... ± tocilizumab; call ... #HemeOnc #Diagnosis
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
age 70 years Symptoms ... Leukemia • Idiopathic ... Myeloproliferative Disease ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Differential Diagnosis ... edema, active urine ... Induced Lupus: • Symptoms ... Hodgkin lymphoma and leukemia ... #Rheumatology
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