11 results
Cerebral Salt Wasting vs SIADH - Pathophysiology 
1) Neurological event
2) Sodium loss from tubules
3) Naturiesis →
Neurological event 2) ... Sodium loss from ... → Increased urine ... Pathophysiology #diagnosis ... #nephrology #hyponatremia
Hyponatremia Differential Diagnosis Algorithm - Utilizing Uric Acid 
ADH promotes Urea/uric acid excretion along with water
Hyponatremia Differential ... Diagnosis Algorithm ... Serum Osmolarity 2) ... 3) Urine Sodium ... Low Uric Acid → SIADH
Volume Based Approach to Hyponatremia
Hypovolemic, Serum uric acid >4
 • Urine Na <20: Extra-renal losses
 •
Based Approach to Hyponatremia ... Renal losses, Cerebral ... uric acid <4 • SIADH ... #algorithm #diagnosis ... #sodium #low #nephrology
Hypernatremia Diagnosis and Workup

Step 1 . Repeat the sodium concentration.
Step 2.  Check plasma osmolality.
NORMAL PLASMA
Hypernatremia Diagnosis ... Repeat the sodium ... Step 2. ... EUVOLEMIC • SIADH ... HYPERVOLEMIC • CHF
Hypernatremia - Differential Diagnosis Workup Algorithm

1) Check Urine Osmolality:
 > 600 mOsm/kg - Implies extrarenal mechanism
Workup Algorithm ... 1) Check Urine ... renal mechanism 2) ... Euvolemic: Diabetes insipidus ... #nephrology #sodium
Physiologic Approach to Hypotonic Hyponatremia
The next time you have a case of hypotonic hyponatremia, give the
normal volume-based algorithm ... Urine Na+K / serum ... , Renal Sodium loss ... Insufficiency, Cerebral ... #differential #diagnosis
A lazy man's classification of hyponatremia
There are two possible approaches to the diagnosis of hyponatremia: .
serum osmolality, urine ... osmolality and urinary sodium ... the patient has SIADH ... or cerebral salt ... #Diagnosis #Hyponatremia
Hypernatremia - Differential Diagnosis and Treatment
Hypernatremia is almost always due to unreplaced water loss (free water
DI; high dilute urine ... water unavailable 2) ... post-obstructive 3) Diabetes Insipidus ... patients at risk for cerebral ... #nephrology #sodium
Primary Polydipsia
Definition: Excessive volitional water intake
Epidemiology:
 • 6-20% of patients with psychiatric disorders - Most commonly
occurs in only 2- ... : Diabetes Insipidus ... Pseudohyponatremia, SIADH ... Osm, Serum Sodium ... , Urine Sodium
Flowchart to diuretic use in acute heart failure.

(A) Congestion with volume overload. 

(B) Treatment algorithm after
(B) Treatment algorithm ... intravenous; SGLT2‐I, sodium–glucose ... linked transporter 2 ... ultrafiltration; UO, urine ... #HeartFailure #Cardiology