15 results
Hyponatremia Differential Diagnosis Algorithm - Utilizing Uric Acid 
ADH promotes Urea/uric acid excretion along with water
Diagnosis Algorithm ... Utilizing Uric Acid ADH ... 2) Urine Osmolarity ... 3) Urine Sodium ... Uric Acid → SIADH
Physiologic Approach to Hypotonic Hyponatremia
The next time you have a case of hypotonic hyponatremia, give the
normal volume-based algorithm ... Urine Na+K / serum ... volume restriction alone ... in SIADH RAAS ... differential #diagnosis #table
Causes of Hypernatremia - Differential Diagnosis Algorithm
Hypernatremia - Excess free water loss, Serum Sodium >145 mmol/L
High
water loss, Serum Sodium ... Osmolality > 300 ... • Hypertonic saline ... mannitol, glucosuria Low ... Urine Osmolality
Hyponatremia (<135 mEq/L) is a common electrolyte abnormality caused by an excess of total body water
, urine sodium concentration ... and urine osmolality ... Measured urine sodium ... #hyponatremia #ADH ... EBV #potomania #SIADH
Hyponatremia Diagnostic Algorithm
1) Check serum osmolality
2) Check urine osmolality
3) ADH Dependent - Check volume status, urine
Algorithm 1) Check ... serum osmolality ... 2) Check urine ... osmolality 3) ADH ... sodium, uric acid
Modified Hyponatremia Algorithm
Hypertonic Hyponatremia: Hyperglycemia, Mannitol, Urologic irrigants
Hypotonic Hyponatremia: 
 • ADH ON (UOsm > 100):
Algorithm Hypertonic ... : • ADH ON (UOsm ... OFF (UNa > 30): SIADH ... Primary polydipsia, Low ... #sodium #nephrology
Volume Based Approach to Hyponatremia
Hypovolemic, Serum uric acid >4
 • Urine Na <20: Extra-renal losses
 •
Based Approach to Hyponatremia ... uric acid <4 • SIADH ... Hypothyroidism, Low ... #algorithm #diagnosis ... #sodium #low #nephrology
Hyponatremia - Diagnosis and Treatment
Hyponatremia is usually caused by the inability to excrete water normally.
majority of cases, ADH ... 2) Is ADH elevated ... Measure urine osmolality ... syndrome. 3% saline ... management #nephrology #sodium
Management of SIADH
Treat underlying cause:
 • Causes can include pain, primary lung pathology, post-operative phenomenon, medications,
promoting passive sodium ... colon 0.9% Normal Saline ... : • If Urine osmolality ... antagonists: • Blocks ADH ... #nephrology #treatment
A lazy man's classification of hyponatremia
There are two possible approaches to the diagnosis of hyponatremia: .
same tests (serum osmolality ... , urine osmolality ... and urinary sodium ... the patient has SIADH ... #Algorithm #Differential