28 results
Cerebral Salt Wasting vs SIADH - Pathophysiology 
1) Neurological event
2) Sodium loss from tubules
3) Naturiesis →
1) Neurological ... event 2) Sodium ... → Increased urine ... Pathophysiology #diagnosis #nephrology ... #hyponatremia #
Hyponatremia Differential Diagnosis Algorithm - Utilizing Uric Acid 
ADH promotes Urea/uric acid excretion along with water
Hyponatremia Differential ... water retention 1) ... Low Uric Acid → SIADH ... Rachel Stern MD #Hyponatremia ... #nephrology #sodium
Volume Based Approach to Hyponatremia
Hypovolemic, Serum uric acid >4
 • Urine Na <20: Extra-renal losses
 •
Based Approach to Hyponatremia ... Renal losses, Cerebral ... uric acid <4 • SIADH ... SatyaPatelMD #Volume #Hyponatremia ... #sodium #low #nephrology
True Hyponatremia Differential Algorithm

Instead (or in addition) of volume status examination, check urine sodium and serum
True Hyponatremia ... and hypervolemic hyponatremia ... - Urine sodium ... low in euvolemic hyponatremia ... kidney_boy #True #Hyponatremia
Modified Hyponatremia Algorithm
Hypertonic Hyponatremia: Hyperglycemia, Mannitol, Urologic irrigants
Hypotonic Hyponatremia: 
 • ADH ON (UOsm > 100):
Modified Hyponatremia ... Hyponatremia: Hyperglycemia ... OFF (UNa > 30): SIADH ... Reset osmostat, Cerebral ... #sodium #nephrology
Hypernatremia Diagnosis and Workup

Step 1 . Repeat the sodium concentration.
Step 2.  Check plasma osmolality.
NORMAL PLASMA
Hypernatremia Diagnosis ... Workup Step 1 ... Repeat the sodium ... mmol/L - true hyponatremia ... renal failure #Hypernatremia
Physiologic Approach to Hypotonic Hyponatremia
The next time you have a case of hypotonic hyponatremia, give the
Approach to Hypotonic Hyponatremia ... case of hypotonic hyponatremia ... Urine Na+K / serum ... Physiologic #Hypotonic #Hyponatremia ... #nephrology
Hyponatremia Differential Diagnosis Table

 • Step 1: Correct for hyperglycemia. Corrected Na = [(glucose - 100)/
Hyponatremia Differential ... Table • Step 1: ... Serum Osm • Urine ... MatthewHoMD #Hyponatremia ... #sodium
Hypernatremia - Differential Diagnosis Workup Algorithm

1) Check Urine Osmolality:
 > 600 mOsm/kg - Implies extrarenal mechanism
Hypernatremia - ... 1) Check Urine ... Extrarenal Hypernatremia ... MatthewHoMD #Hypernatremia ... #nephrology #sodium
A lazy man's classification of hyponatremia
There are two possible approaches to the diagnosis of hyponatremia: .
classification of hyponatremia ... the diagnosis of hyponatremia ... serum osmolality, urine ... or cerebral salt ... #Diagnosis #Hyponatremia