58 results
Oncologic Emergencies - Differential Diagnosis Framework

HEMATOLOGIC ONCOLOGIC EMERGENCIES:
Hyperviscosity Syndrome:
 • Spontaneous bleeding
 • Shortness of breath
- Differential Diagnosis ... Hyperviscosity Syndrome ... Vomiting, decreased urine ... coma SIADH: • Hyponatremia ... #differential #diagnosis
Hyponatremia - Diagnosis and Treatment
Hyponatremia is usually caused by the inability to excrete water normally.
Hyponatremia - Diagnosis ... Measure urine osmolality ... demyelination syndrome ... vaptans (HF/liver disease ... #Treatment #management
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... and Management ... old, ~10,000 new cases ... Myelodysplastic #Syndrome ... #hematology #oncology
Multiple Myeloma and Monoclonal Gammopathies
C - HyperCalcemia- calcium > 11 mg/dL / >1 mg/dL the ULN
R
Causes of false- ... amyloidosis Other causes ... plasmacytoma, POEMs syndrome ... Gammopathies #MGUS #diagnosis ... #hematology #oncology
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
Summary Causes ... Dermatomyositis Clinical ... Hyperuricemia • Hyponatremia ... of underlying disease ... #Management #causes
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Clinical Presentation ... Fever is the main clinical ... 10,000 ng/mL • Hyponatremia ... #Diagnosis #Management ... #Hematology #Rheumatology
Adrenal Insufficiency - Diagnosis and Management Summary
Primary Adrenal Insufficiency:
Most Common Cause in the US: Autoimmune Adrenalitis
Other
and Management ... or metastatic disease ... secondary AI, hyponatremia ... , infiltrative diseases ... hypophysitis, Sheehan's syndrome
Tumor Lysis Syndrome - Workup and Management

Initial workup: BMP, Serum uric acid, LDH, Urine output, Consider
Tumor Lysis Syndrome ... uric acid, LDH, Urine ... Treatment of Clinical ... #diagnosis #management ... #oncology
Syncope is a sudden, transient loss of consciousness, which is thought to be secondary to cerebral
structural heart disease ... carotid sinus syndrome ... further guide management ... should be guided by clinical ... the underlying disease
Monoclonal Gammopathy of Clinical Significance (MGUS) - Differential Diagnosis

Neurologic-Centered:
 (+) Systemic Features: POEMS, AL amyloid, Cryoglobulinemia
Gammopathy of Clinical ... - Differential Diagnosis ... capillary leak syndrome ... Ig deposition disease ... #hematology #oncology