12 results
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
CNS Manifestations ... Erythematosus (SLE) Clinical ... autoantibodies that will cause ... permeability Diagnosis ... #neurology #rheumatology
CNS Infection in HIV / AIDS - Differential Diagnosis Framework

Principles of HIV-Associated CNS Opportunistic Infections:
 •
- Differential Diagnosis ... should be based on clinical ... Antimicrobial treatment ... Demyelinating disease caused ... opportunistic #InfectiousDiseases
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
- Differential Diagnosis ... Management Summary Causes ... Dermatomyositis Clinical ... Weakness - Dark urine ... Hyperuricemia • Hyponatremia
Invasive Aspergillus (IA) - Diagnosis and Management
Aspergillus is ubiquitous in nature. Most invasive infections are caused
infections are caused ... HIV/AIDS, CGD) Clinical ... Rhinosinusitis, CNS ... #Management #treatment ... #fungal #infectiousdiseases
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
nervous system (CNS ... 10,000 ng/mL • Hyponatremia ... Treatment: • Corticosteroids ... Activation #Syndrome #Diagnosis ... #Rheumatology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
organ damage Clinical ... Thromboembolism (7%) • CNS ... Treat primary cause ... #Coagulation #diagnosis ... #causes #treatment
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis

The most common causes of hyperlactatemia are usually:
- Differential Diagnosis ... excretion (e.g., urine ... / hypoxemia -> focus ... perfusion - shock->treatments ... before beginning treatment
Mycoses

HISTOPLASMOSIS
• Inhalation of conidia → Yeast → travel to lymph nodes → spread in body
• Bird
pulmonary symptoms • Rheumatologic ... has five major clinical ... especially the CNS ... MC: CNS CSF: • ... ) #Mycoses #InfectiousDiseases
Blastomycosis Summary

Pathogen: 
 • Dimorphic fungus - Blastomyces dermatitidis or Blastomyces gilchristii.
 • The fungus lives
adjacent to the focus ... fluid, BAL, CSF, urine ... Treatment: ... Moderate-severe • CNS ... #infectiousdiseases
Clarkson’s Disease - Capillary leak syndrome
Epidemiology: Roughly 150 published cases, Median age 50 years, No sex
150 published cases ... Relapsing-remitting course +++ Clinical ... hypoalbuminemia with no urine ... leak #syndrome #diagnosis ... #rheumatology