10 results
Hyperuricemia - Differential Diagnosis Algorithm
Primary - Over-production
     • Increased turnover of nucleotides
Primary
Hyperuricemia - Differential ... diet Secondary ... • Diabetic acidosis ... • Chronic renal ... endocrinology #causes
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis

The most common causes of hyperlactatemia are usually:
Acidosis - Differential ... excretion (e.g., urine ... perfusion - shock->treatments ... before beginning treatment ... #Differential #
Types of Renal Calculi

Calcium oxalate
 - Interstitial apatite plaque, Low urine volume, Increased urinary calcium excretion,
tubular acidosis ... tubular acidosis ... - Antiviral treatment ... #stones #differential ... #diagnosis #causes
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
Rhabdomyolysis - Differential ... Management Summary Causes ... Dermatomyositis Clinical ... Weakness - Dark urine ... Hyperuricemia • Hyponatremia
5-Oxoprolinuria
What is it:
 • Aka pyroglutamic acidosis, Intermediate in γ-glutamyl cycle
 • Amino acid transport and
Aka pyroglutamic acidosis ... • Liver and renal ... undetectable • Lactic ... high index of clinical ... turnaround) • le urine
Thiamine Deficiency - Differential Diagnosis Framework and Clinical Manifestations

Causes of Thiamine Deficiency:
 • Poor intake:
	- Diets
Thiamine Deficiency - Differential ... Framework and Clinical ... Manifestations Causes ... also seen • Lactic ... acidosis may not
Causes of Hypokalemia
Transcellular Shifts:
 - Alkalosis, Increased plasma insulin (treatment of diabetic ketoacidosis), ß-Adrenergic agonists, Hypokalemic
Causes of Hypokalemia ... plasma insulin (treatment ... hyperaldosteronism, Secondary ... tubular acidosis ... #differential #
Anion Gap Metabolic Acidosis (AGMA) Differential Diagnosis - MUDPILES and GOLDMARK

M - Methanol
U - Uremia
D -
(AGMA) Differential ... INH, Iron L - Lactic ... - Aspirin R - Renal ... and is usually clinically ... also emerged as causes
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
other diseases • Secondary ... Hypocomplementemia • Can cause ... salivary ducts Clinical ... tubular acidosis ... Adenocarcinoma Treatment
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
tubule (DCT) Clinical ... Hypocalciuria (spot urine ... ratio 0.5%) Differential ... tubular acidosis ... Rhabdomyolysis Treatment