46 results
Hyponatremia Differential Diagnosis Algorithm - Utilizing Uric Acid 
ADH promotes Urea/uric acid excretion along with water
Hyponatremia Differential ... Osmolarity 2) Urine ... Osmolarity 3) Urine ... Sodium 4) Serum ... Low Uric Acid → SIADH
Cerebral Salt Wasting vs SIADH - Pathophysiology 
1) Neurological event
2) Sodium loss from tubules
3) Naturiesis →
Salt Wasting vs SIADH ... Neurological event 2) Sodium ... → Increased urine ... #SaltWasting #SIADH ... diagnosis #nephrology #hyponatremia
True Hyponatremia Differential Algorithm

Instead (or in addition) of volume status examination, check urine sodium and serum
examination, check urine ... sodium and serum ... uric acid: - Urine ... sodium low, uric ... - Urine sodium
Volume Based Approach to Hyponatremia
Hypovolemic, Serum uric acid >4
 • Urine Na <20: Extra-renal losses
 •
Based Approach to Hyponatremia ... uric acid >4 • Urine ... uric acid <4 • SIADH ... SatyaPatelMD #Volume #Hyponatremia ... algorithm #diagnosis #sodium
Modified Hyponatremia Algorithm
Hypertonic Hyponatremia: Hyperglycemia, Mannitol, Urologic irrigants
Hypotonic Hyponatremia: 
 • ADH ON (UOsm > 100):
Modified Hyponatremia ... Algorithm Hypertonic Hyponatremia ... OFF (UNa > 30): SIADH ... , Medications (diuretics ... Algorithm #diagnosis #sodium
Hypernatremia Diagnosis and Workup

Step 1 . Repeat the sodium concentration.
Step 2.  Check plasma osmolality.
NORMAL PLASMA
Hypernatremia Diagnosis ... Repeat the sodium ... mmol/L - true hyponatremia ... EUVOLEMIC • SIADH ... renal failure #Hypernatremia
Physiologic Approach to Hypotonic Hyponatremia
The next time you have a case of hypotonic hyponatremia, give the
volume-based algorithm Urine ... restriction alone in SIADH ... Present (Uosm ≥100): SIADH ... , Renal Sodium loss ... diagnosis #table #sodium
A lazy man's classification of hyponatremia
There are two possible approaches to the diagnosis of hyponatremia: .
classification of hyponatremia ... the diagnosis of hyponatremia ... serum osmolality, urine ... osmolality and urinary sodium ... the patient has SIADH
Management of SIADH
Treat underlying cause:
 • Causes can include pain, primary lung pathology, post-operative phenomenon, medications,
Management of SIADH ... post-operative phenomenon, medications ... promoting passive sodium ... Saline: • If Urine ... #Management #hyponatremia
SIADH Treatment Options
1. Treat underlying cause of SIADH: Pain, Primary lung pathology, Post-operative phenomenon, Medications, Basically
Post-operative phenomenon, Medications ... promoting passive sodium ... 0.9% NS • If Urine ... Hypotension, Increased urine ... #Management #hyponatremia