8 results
Spectrum of Glomerular Diseases
Nephrotic - Mechanism:
 • Injury to podocytes
 • Changed architecture: Scanning. Deposition of
Diseases Nephrotic ... • Breaks in GBM ... #Diseases #differential ... spectrum #diagnosis #nephrology ... #comparison
Nephritic vs Nephrotic Syndrome

Step 1: If the patient has hematuria and/or proteinuria, think about nephrotic/nephritic syndromes.
Step
Nephritic vs Nephrotic ... the patient have glomerular ... hematuria (RBC casts ... #Syndrome #Comparison ... #Algorithm #Nephrology
Glomerular Diseases - Nephritic and Nephrotic Syndromes

Nephritic syndrome—due to GBM disruption. 
Hypertension. t BUN and creatinine.
Glomerular Diseases ... to GBM disruption ... RBC casts in urine ... #Diseases #Nephritic ... #Proteinuria #Nephrology
Summary of characteristic abnormalities of selected glomerular diseases
Light Microscopy (LM) - Immunofluorescence Microscopy (IM) - Electron
Immunofluorescence Microscopy (IM ... ) Haematuria/nephritis ... Haemolytic-uraemic syndrome Nephrotic ... #diseases #nephrology ... #pathology #comparison
Causes of Hematuria - Differential Diagnosis Algorithm
Red blood cells on urine microscopy. Must exclude false positives
Causes of Hematuria ... Differential Diagnosis Algorithm ... disease • ... Hereditary nephritis ... • Pauci-immune disease
Algorithm - Approach to the differential diagnosis of the patient presenting with overt glomerular proteinuria. CMV
Algorithm - Approach ... Cytomegalovirus; GBM ... impairment), heart disease ... Nephrocalcinosis causes ... #syndrome #nephrology
Causes of Proteinuria - Differential Diagnosis Algorithm
Persistent Proteinuria >150mg/d protein present on repeat testing including overnight
Causes of Proteinuria ... Differential Diagnosis Algorithm ... Minimal change disease ... #Proteinuria #Nephrology ... #Causes
Membranoproliferative Glomerulonephritis (MPGN) AKA: Mesangiocapillary GN
 • Active Urine Sediment (dysmorphic RBC, RBC casts, +/- proteinuria)
dysmorphic RBC, RBC casts ... (Dense deposit disease ... immune deposits on EM ... glomerulopathy, radiation nephritis ... Glomerulonephritis #MPGN #nephrology