10 results
Summary of characteristic abnormalities of selected glomerular diseases
Light Microscopy (LM) - Immunofluorescence Microscopy (IM) - Electron
(IM) - Electron ... Microscopy (EM) ... RPGN • Anti-GBM ... #diseases #nephrology ... #pathology #comparison
Spectrum of Glomerular Diseases
Nephrotic - Mechanism:
 • Injury to podocytes
 • Changed architecture: Scanning. Deposition of
Spectrum of Glomerular ... Diseases Nephrotic ... • Breaks in GBM ... spectrum #diagnosis #nephrology ... nephritic #nephrotic #comparison
Causes of acute kidney injury (AKI). AKI is classified into pre-renal, renal, and post-renal causes. Renal
, renal, and post-renal ... vascular supply; glomerular ... and interstitial disease ... GBM, Glomerular ... Causes #Sites #Nephrology
Pulmonary Renal Syndrome

Definition: Diffuse alveolar hemorrhage + Glomerulonephritis
Presentation (Pulmonary and renal manifestations can occur weeks apart):
polyangiitis, Microscopic ... sclerosis • Anti-Glomerular ... anti-ANCA ab, anti-GBM ... biopsy By Tess Litchman ... differential #diagnosis #nephrology
Acute Kidney Injury (AKI) - Differential Diagnosis Framework

PRE-Renal AKI:
 • Hypovolemia
 • Congestion
 • Medications
 •
• Vascular • Glomerular ... Immune-complex disease ... , Anti-GBM • Tubular ... Bilateral ureteral disease ... Differential #Diagnosis #nephrology
Causes of Proteinuria - Differential Diagnosis Algorithm
Persistent Proteinuria >150mg/d protein present on repeat testing including overnight
• Drugs Glomerular ... proliferative • Anti-GBM ... polyangiitis (GPA) / microscopic ... Minimal change disease ... #Proteinuria #Nephrology
Anti-GIomeruIar Basement Membrane Disease (Goodpasture's Disease)

What is it? A small vessel vasculitis with circulating antibodies directed
(Goodpasture's Disease ... directed against the glomerular ... Diagnosis: • Anti-GBM ... weeks By Tess Litchman ... AntiGBM #diagnosis #nephrology
Pulmonary Renal Syndromes - OnePager Summary
Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
life-threatening diseases ... Inflammatory eye disease ... antibody, Anti-GBM ... usually low in anti-GBM ... hypercellular glomeruli
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
pulmonary and renal ... PR3-ANCA): • Microscopic ... glomerulonephritis) • Anti-GBM ... : - Kidneys: glomerular ... • Urinalysis (Renal
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
pulmonary and renal ... atherosclerotic disease ... • Kidneys: Non-glomerular ... (PR3-ANCA)): Microscopic ... pain and GN Anti-GBM