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diagnosis differential algorithm pathology proteinuria pulmonary rheumatology syndrome vasculitis anti antigbm basement classification clinical comparison disease diseases electronmicroscopy glomerulus goodpastures
Causes of Hematuria - Differential Diagnosis Algorithm Red blood cells on urine microscopy. Must exclude false positives
• Calculi Glomerular ... epithelial side of glomerular ... nephropathy • Thin GBM ... endothelial side of glomerular ... ) • Anti-GBM
Summary of characteristic abnormalities of selected glomerular diseases Light Microscopy (LM) - Immunofluorescence Microscopy (IM) - Electron
abnormalities of selected glomerular ... (IM) - Electron ... Microscopy (EM) ... RPGN • Anti-GBM ... polyangiitis #glomerular
Stage IV Glomerulonephritis on Electron Microscopy This image shows acellular scanning EM of glomerular capillary loops from
on Electron Microscopy ... of glomerular capillary ... completely bridged GBM ... #glomerulus #MGN ... SEM #clinical #nephrology
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 Anti-GIomeruIar Basement Membrane Disease (Goodpasture's Disease) What is it? A small vessel vasculitis with circulating antibodies directed
Anti-GIomeruIar ... directed against the glomerular ... Diagnosis: • Anti-GBM ... PulmPEEPs #Anti #GIomeruIar ... AntiGBM #diagnosis #nephrology
Pulmonary Renal Syndrome Definition: Diffuse alveolar hemorrhage + Glomerulonephritis Presentation (Pulmonary and renal manifestations can occur weeks apart):
alveolar hemorrhage + Glomerulonephritis ... polyangiitis, Microscopic ... sclerosis • Anti-Glomerular ... anti-ANCA ab, anti-GBM ... differential #diagnosis #nephrology
Algorithm - Approach to the differential diagnosis of the patient presenting with overt glomerular proteinuria. CMV
presenting with overt glomerular ... Cytomegalovirus; GBM ... = glomerular basement ... Nephrocalcinosis causes ... differential #diagnosis #glomerular
Causes of Proteinuria - Differential Diagnosis Algorithm Persistent Proteinuria >150mg/d protein present on repeat testing including overnight
• Drugs Glomerular ... proliferative • Anti-GBM ... polyangiitis (GPA) / microscopic ... #Proteinuria #Nephrology ... Diagnosis #Algorithm #Causes
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
PR3-ANCA): • Microscopic ... tract, and often causes ... ) • Anti-GBM - ... Vasculitis - Skin, glomeruli ... : - Kidneys: glomerular
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
• Kidneys: Non-glomerular ... (PR3-ANCA)): Microscopic ... , pauci-immune glomerulonephritis ... tract, and often causes ... pain and GN Anti-GBM
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