90 results
Approach to Von Willebrand disease (VWD)

By Matthew Ho, MD PhD @MatthewHoMD

#VWD #Von #Willebrand #VonWillebrand #disease #hematology
Willebrand disease (VWD ... MatthewHoMD #VWD ... VonWillebrand #disease #hematology ... #algorithm #diagnosis
Inherited Qualitative Platelet Defects
Bernard-Soulier Syndrome
 • Defect of adhesion due to a lack of GP Ib/IX/V
Qualitative Platelet Defects ... of GP Ib/IX/V [vWF ... Thrombasthenia • Defect ... α-granules (contains vWF ... differential #diagnosis #hematology
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm
Thrombocytopenia - Quantitative Defect
 • Decreased Production
 •
Differential Diagnosis Algorithm ... - Quantitative Defect ... - Qualitative Defect ... Iatrogenic) • Liver ... #Causes #Hematology
Focused evaluation algorithm for acute liver injury

#Liver #Injury #Acute #Evaluation #Algorithm #Diagnosis #Hepatology
Focused evaluation algorithm ... for acute liver ... injury #Liver ... Acute #Evaluation #Algorithm ... #Diagnosis #Hepatology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
PURPURA: Platelet Defects ... syndrome Coagulation Defects ... deficiency • Liver ... Willebrand disease (VWD ... Differential #Diagnosis #hematology
Cardiac Murmurs and Maneuvers

An algorithm demonstrating the effect of various maneuvers on systolic murmurs. 
TR, tricuspid
Maneuvers An algorithm ... demonstrating the effect ... aortic stenosis; VSD ... ventricular septal defect ... The effect of squatting
Causes of Thrombocytosis - Differential Diagnosis Algorithm
Spurious:
 • Artifact (redo CBC)
Autonomous:
 • Essential thrombocytosis
 • Polycythemia
Differential Diagnosis Algorithm ... Non malignant hematologic ... ITP • Rebound effect ... Differential #Diagnosis #Algorithm ... #Causes #Hematology
Platelet disorders and Aggregometry
Glanzmann Thrombasthenia
 • Defective aggregation to all agonists except ristocetin
 • Normal platelet,
also be seen in vWD ... differentiate vWD ... BS by measuring vWF ... with qualitative defects ... Platelet #disorders #hematology
Causes of Acute Liver Injury - Differential Diagnosis
Hepatocellular - Liver Parenchyma
 • Infectious: Hepatitis C, A,
Causes of Acute Liver ... Hepatocellular - Liver ... , Sickle Cell, VOD ... Causes #Acute #algorithm ... #hepatology
Drug-Induced Liver Injury - Pathophysiology
Indirect
Idiosyncratic
Direct

BWH Medicine Chiefs @BrighamChiefs

#DILI #DrugInduced #Liver #Injury #Pathophysiology #hepatology
Drug-Induced Liver ... Idiosyncratic Direct ... #DrugInduced #Liver ... Pathophysiology #hepatology