1848 results
Approach to Von Willebrand disease (VWD)

By Matthew Ho, MD PhD @MatthewHoMD

#VWD #Von #Willebrand #VonWillebrand #disease #hematology
Willebrand disease (VWD ... MatthewHoMD #VWD
Platelet disorders and Aggregometry
Glanzmann Thrombasthenia
 • Defective aggregation to all agonists except ristocetin
 • Normal platelet,
also be seen in vWD ... differentiate vWD ... BS by measuring vWF
Liver Abscess
•	Pyogenic abscess, accounts for 80% of abscess.
•	Amebic abscess due to Entamoeba histolytica, accounts for 10%.
•	Fungal
Liver Abscess • ... Pyogenic abscess ... accounts for 80% of abscess ... • Amebic abscess ... • Fungal abscess
Liver Abscess on POCUS
24yo healthy F to ED w/rigors &DCed. 2/2 blood cx + for fusobacterium,
Liver Abscess on ... this 2x2cm liver abscess ... EUSmkh #Liver #Abscess ... POCUS #Clinical #Ultrasound
Point-of-care Ultrasound for Diagnosis of Abscess in Skin and Soft Tissue Infections

1. POCUS is more accurate
Point-of-care Ultrasound ... for Diagnosis of Abscess ... distinguishing abscess ... in cases where abscess ... for identifying abscess
Liver Abscess on POCUS Ultrasound

Fever and RUQ pain/tenderness isn't always chole. In this patient population make
Liver Abscess on ... POCUS Ultrasound ... spontaneous liver abscess ... #POCUS #Liver #Abscess
Antibiotic Tissue Penetration

Blood Brain Barrier: Penicilins (IV), 3rd & 4th generation Cephalosporins (IV), Meropenem, TMP-SMX, Metronidazole,
hydrophilic, low Vd ... Vancomycin (low Vd ... Fluoroquinolones Poor Abscess
Hemoptysis - Differential Diagnosis Framework
Massive Hemoptysis: >150-300 mL in 24h
Airway disease: 
 • Bronchitis, Bronchiectasis, Malignancy
Necrotizing PNA, Abscess ... Coagulopathy: DIC, vWD
Bleeding manifestations 
Petechiae are small, flat, red, discrete areas of skin bleeding that are typically <2
Diagnosis VWF ... (Quantity of VWF ... considered to be low) VWF ... of this plasma VWF ... (differentiate VWD
Patch dehiscence (post surgical correction of congenital VSD) on Echocardiogram

Ivan Stankovic, MD, PhD @Ivan_Echocardio

#VSD #Patch #dehiscence
of congenital VSD ... Ivan_Echocardio #VSD