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diagnosis hepatology liver differential lfts chemistry drug elevation functiontest gastroenterology idiosyncratic induced injury interpretation management rvalue
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI) DILI Types: • Intrinsic - predictable, dose dependent
Liver Injury (DILI ... ) DILI Types: ... Calculate R-Value ... gastroenterology #algorithm ... gastroenterology #hepatology
Liver Function Test (LFTs) Elevation AST - Cardiac and skeletal muscle, kidney, brain ALT - More specific for
abnormality vs bone Bili ... ALP ≥ 2x ULN R Value ... LFTs #Elevation #Transaminitis ... #diagnosis #hepatology
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Interpretation of LFTs R-value ... Unconjugated Bili ... > 90% of Total Bili ... #differential #Hepatology ... #transaminitis
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