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management hematology neurology differential oncology clinical algorithm pathophysiology radiology syndromes aids barre bee caudaequina classification cns disorders guillain hiv leukemia
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
high WBC count cause ... priapism • Lab values ... sudden death • Lab values ... #TLS #diagnosis ... #management #hematology
BEE Syndromes - Immune-mediated conditions affecting the brain, eye, and ear Visual or auditory symptoms in conjunction
Visual or auditory symptoms ... conjunction with symptoms ... and treatment can ... Inflammatory causes ... #neurology #inflammatory
BEE Syndromes - Non-inflammatory Causes Immune-mediated conditions affecting the Brain, Eye, and Ear Visual or auditory symptoms in
Non-inflammatory Causes ... conjunction with symptoms ... and treatment can ... neuropathy (LHON) plus MRI ... consistent with MS
Tolosa-Hunt Syndrome What? • Unilateral orbital/retrobulbar pain • Paresis of the cranial nerves Ill, IV, VI •
fissure or orbit (MRI ... ) Treatment: • ... resolution of the symptoms ... #TolosaHunt #neurology ... #diagnosis
Posterior Ankle Impingement (Os Trigonum) Syndrome - MSK Radiology Imaging Findings: • Os trigonum which has marrow
(Os Trigonum) Syndrome ... - MSK Radiology ... Case description ... flexion but no symptoms ... #msk
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... old, ~10,000 new cases ... only curative treatment ... #Management #treatment ... #hematology #oncology
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
workup for specific symptoms ... for secondary causes ... glucocorticoid treatment ... #Differential #diagnosis ... #hematology #eosinophilia
Cauda Equina Syndrome Causes: • Large lumbar degenerative disc herniation (central) • Severe lumbar spondylosis • Neoplasm
Cauda Equina Syndrome ... Causes: • Large ... suspected, immediate MRI ... #MSK #pathophysiology ... #diagnosis #symptoms
Multiple Myeloma and Monoclonal Gammopathies C - HyperCalcemia- calcium > 11 mg/dL / >1 mg/dL the ULN R
focal lesions on MRI ... Causes of false- ... plasmacytoma, POEMs syndrome ... Gammopathies #MGUS #diagnosis ... #hematology #oncology
Cauda Equina Syndrome Overview Cauda Equina Syndrome: • Prevalence: 1:33,000-100,000 ppl/yr • Incidence: 1.5-3.4 million ppl/yr •
spine L1-L5 Symptoms ... - Emergency Causes ... Imaging studies: • MRI ... axial T1 and T2 Treatment ... #causes #neurology
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