11 results
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... HELLP - Grafts, Valves ... Defects, Drugs, Liver ... Haptoglobin ↓ - Lactate ... #Diagnosis #hematology
Maculopapular - Diagnostic Algorithm
Pathophysiology:
- Catch-all term with a wide range of potential pathophysiologic mechanisms and causative
- Pathophysiology ... Ill-appearing, vital sign ... #Diagnosis #Dermatology ... Targetoid #Algorithm #Differential ... #Ddxof
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis

The most common causes of hyperlactatemia are usually:
Lactic Acidosis - Differential ... glucose by the liver ... to bolus these values ... 30mmHg) - Severe anemia ... Acidosis #Elevation #Differential
Abnormal liver function tests algorithm.
 This figure details the initial response to abnormal liver blood tests.
Abnormal liver function ... clinical symptoms/signs ... normalised ratio; LDH, lactate ... Abnormal #Algorithm #Hepatology ... #Differential #
Bandemia Overview

Normal: < 1%
Clinically significant: > 10%

Band neutrophils are slightly less mature than segmented neutrophils and
Neutrophil (Normal) Differential ... appreciate the value ... #differential # ... neutrophil #WBC #CBC #hematology ... #pathophysiology
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura

Activity of von Willebrand factor-cleaving protease activity - A
activity - A low value ... If the value is ... elevation Serum lactate ... WBC count and differential ... Diagnosis #Workup #Hematology
Elevated Lactate Dehydrogenase (LDH) - Differential Diagnosis Framework

LDH is a cytoplasmic enzyme present in tissues throughout
Elevated Lactate ... Dehydrogenase (LDH) - Differential ... RBCs, muscle, liver ... - Prosthetic valves ... disease #LDH #Lactate
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework

VENOUS THROMBOSIS

 • Acquired Risk Factors:
	- >48 hours
Arterial Thrombosis - Differential ... Syndrome, Ischemic Liver ... from prosthetic valves ... Venous #Arterial #pathophysiology ... #hematology #differential
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
65 years PBC Pathophysiology ... cholestasis → Cirrhosis/Liver ... failure PBC Signs ... or higher • Liver ... bile ducts Differential
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
systemic sx + signs ... or sed rate): Value ... very remarkable w/differential ... GCA, but normal values ... GCA #Temporal #Signs