13 results
Cholestatic Liver Disease: Primary Biliary Cirrhosis vs Primary Sclerosing Cholangitis

#pathophysiology #pbc #psc #hepatology #comparison
Cholestatic Liver ... Disease: Primary ... Biliary Cirrhosis ... Cholangitis #pathophysiology ... #pbc #psc #hepatology
Diagnosis of ascites according to the serum ascites albumin gradient (SAAG)
SAAG ≥ 1.1:
 - Ascitic protein
) SAAG ≥ 1.1: ... protein ≤ 2.5 g/dL: Cirrhosis ... syndrome, Massive liver ... < 1.1: Biliary ... albumin #gradient #hepatology
Primary Biliary Cirrhosis - Pathophysiology
Environmental Risk Factors: Geographic location, Smoking, Microbial triggers, Xenobiotics, Nail polish
Epigentics Risk
Primary Biliary ... Cirrhosis - Pathophysiology ... Cholestasis #PBC #Primary ... #Biliary #Cirrhosis ... #hepatology
Common Etiologies of Cirrhosis

Inflammation

 - Hepatitis B (15 percent)

 - Hepatitis C (47 percent)

 - Schistosomiasis
Etiologies of Cirrhosis ... congenital - Primary ... biliary cirrhosis ... Nonalcoholic fatty liver ... #Differential #Hepatology
Primary Biliary Cirrhosis - Diagnosis Algorithm
Symptoms: Fatigue, Pruritus, Right upper quadrant discomfort
Signs: Jaundice, Xanthelasmata, Hepatomegaly
Associated history:
Primary Biliary ... Cirrhosis - Diagnosis ... Liver biopsy findings ... #Biliary #Cirrhosis ... Diagnosis #Algorithm #hepatology
Portal Hypertension - Differential Diagnosis
Portal Pressure = the pressure difference between the pressure in the portal
HTN: ascites (SAAG ... sarcoidosis) • Liver ... pregnancy • Primary ... biliary cirrhosis ... Diagnosis #causes #hepatology
Hepatomegaly - Differential Diagnosis Algorithm
Malignant
 • Primary Carcinoma
 • Metastases
 • Lymphoma
 • Leukemia
 • Polycythemia
Malignant • Primary ... Non-Malignant • Fatty Liver ... Cholangitis • Primary ... Biliary Cirrhosis ... Algorithm #Causes #Hepatology
Causes of Ascites
Normal Peritoneum
Portal hypertension (SAAG > 1.1 g/dL)
  1. Hepatic congestionl
Liver disease ... - Cirrhosis ... - Acute fatty liver ... carcinomatosis - Primary ... #differential #hepatology
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
Primary Biliary ... 65 years PBC Pathophysiology ... /Liver failure ... #Biliary #Cirrhosis ... diagnosis #workup #hepatology
The Liver Consult Primer - Guide to calling a consult
HPI:
 - Start with reason for consult
Primer - Guide ... Gl History - Cirrhosis ... Consultation #GIConsult #Primer ... Calling #Referral #Hepatology ... #Gastroenterology