41 results
Causes of Hypokalemia - Differential Diagnosis Algorithm
Defining the cause of hypokalemia starts by measuring urinary K
Causes of Hypokalemia ... starts by measuring ... , Gitelman's syndrome ... #hypokalemia ... algorithm #causes #nephrology
Potassium Binders for Management of Hyperkalemia
 • SPS - Sodium polystyrene sulfonate
 • Patiromer (veltassa)
 •
of Hyperkalemia ... • SPS - Sodium ... #Hyperkalemia # ... #pharmacology #table ... #comparison #nephrology
Drugs associated with hypokalemia and hypomagnesemia

Hypokalemia
- Shift from extracellular fluid to intracellular fluid compartment
  -
associated with hypokalemia ... hypomagnesemia Hypokalemia ... overdose) - Sodium ... renal Fanconi syndrome ... differential #diagnosis #nephrology
Hyperkalemia Treatment Options
Stabilize cardiac membrane:
 • IV Calcium (peaks 5-10 minutes)
Decrease potassium concentration:
 • IV Fluids
Shift
Hyperkalemia Treatment ... 90 minutes) • Sodium ... LouLectures #Hyperkalemia ... #management #potassium ... #nephrology
Gitelman Syndrome Pathophysiology
Gitelman Syndrome is a rare autosomal recessive salt-losing tubulopathy with a prevalence of 1-
Gitelman Syndrome ... Pathophysiology Gitelman Syndrome ... thiazide-sensitive sodium-chloride ... H+ secretion → Hypokalemia ... Pathophysiology #nephrology
Emergency Therapy of Hyperkalemia
Therapy - Dose and Route - Onset of Action - Duration of Effect
Emergency Therapy of Hyperkalemia ... glucose, Furosemide, Sodium ... Hemodialysis #Hyperkalemia ... #management #pharmacology ... #table #treatment
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
thiazide-sensitive sodium ... thiazide-sensitive sodium ... Hypocalciuria (spot ... #diagnosis #nephrology ... #management #pathophysiology
Modified Hyponatremia Algorithm
Hypertonic Hyponatremia: Hyperglycemia, Mannitol, Urologic irrigants
Hypotonic Hyponatremia: 
 • ADH ON (UOsm > 100):
ON (UNa < 30): Hypovolemia ... Cirrhosis, Nephrotic syndrome ... Algorithm #diagnosis #sodium ... #nephrology
Treatment of Hyperkalemia
Membrane Stabilization
 • Calcium Gluconate (10%)
 • Hypertonic (3%) Normal Saline
Shifters:
 • Insulin (Short
Treatment of Hyperkalemia ... : • Insulin (Short ... Furosemide • Sodium ... #Management #Treatment ... Interventions #Table
Inherited Defects in Kidney Tubule Epithelial Cells

Renal glucosuria - Na+-dependent glucose cotransporter
Cystinuria - Amino acid transporter
Bartter
limb Gitelman syndrome ... cell epithelial sodium ... of epithelial sodium ... Defects #Kidney #Nephrology ... #Differential #Table