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differential hematology management causes algorithm symptoms workup erythematosus lupus criteria oncology sclerosis sle treatment abnormal classification clinical dermatology disorders monoclonal
Pulmonary Renal Syndrome Definition: Diffuse alveolar hemorrhage + Glomerulonephritis Presentation (Pulmonary and renal manifestations can occur weeks apart):
Differential Diagnosis ... Immune Complex: Systemic ... testing: anti-ANCA ... , biopsy By Tess ... #nephrology
Systemic Sclerosis (Scleroderma) Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs 3
autoimmune disease ... skin thickening Signs ... Scleroderma #SSc #rheumatology ... #diagnosis #signs ... #symptoms #testing
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
Initial screening test ... block • Sjogren syndrome ... polymyositis overlap syndrome ... #SLE #Summary #diagnosis ... #rheumatology #
Parinaud's Syndrome What? - Impaired upgaze - Light-near dissociation - Convergence retraction nystagmus - Eyelid retraction (Collier's
Parinaud's Syndrome ... Hydrocephalus → "setting ... disease (stroke ... #diagnosis #pineal ... #neurology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
Systemic disease ... skin injury) • Neurologic ... is a skin prick test ... #signs #symptoms ... #rheumatology #
Parinaud's syndrome What? • Light-near dissociation (tectal pupils) • Convergence retraction nystagmus • Eyelid retraction (Collier's sign)
Parinaud's syndrome ... Hydrocephalus -> "setting ... sun" sign • Vascular ... disease (stroke ... #neurology #diagnosis
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Demyelinating syndromes ... pain (20%) Renal disease ... erythematosus #signs ... #symptoms #diagnosis ... #rheumatology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Macrophage Activation Syndrome ... highly inflammatory disease ... Liver function tests ... #Diagnosis #Management ... #Hematology #Rheumatology
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... affected joint • Systemic ... (to support a diagnosis ... laboratory #workup #diagnosis ... #testing #Rheumatology
Causes of Bradykinetic Movement Disorders - Differential Diagnosis Algorithm Parkinson's Disease (TRAP): • Resting Tremor • Cogwheel Rigidity • Akinesia/Bradykinesia •
Algorithm Parkinson's Disease ... (TRAP): • Resting ... backwards Multiple System ... • Cerebellar signs ... MovementDisorders #Neurology
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