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rheumatology dermatology oncology neurology treatment alopecia anemia cardiology chronic disease hairloss signs agglutinin alternating antibodies antinuclear arteritis bariatric behcet bilateral
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Constitutional Syndromes ... Constitutional Syndromes ... marrow-failure syndromes ... myelodysplastic syndrome ... #diagnosis #management
Causes of Neutropenia - Differential Diagnosis Neonate: - Infection - by far the most common cause -
neutropenia, Kostmann syndrome ... Chediak-Higashi syndrome ... white blood cell aplasia ... #diagnosis #causes ... #hematology
Causes of Fatigue - Differential Diagnosis Algorithm Endocrine • Hypo/Hyperthyroidism • Diabetes • Pituitary Insufficiency • Adrenal
Diagnosis Algorithm ... Neoplastic / Hematologic ... • Malignancy Infectious ... Chronic Fatigue Syndrome ... #Diagnosis #Algorithm
Hypereosinophilia Syndrome (HES) - Diagnosis and Management Definition: An absolute eosinophil count (AEC) greater than 1500 and
Hypereosinophilia Syndrome ... and Management ... clinical manifestations ... Hypereosinophilia #Syndrome ... #hematology #differential
Vancomycin induced Leukocytoclastic Vasculitis (LCV) of the Hand 70 M vertebral osteomyelitis on vancomycin and cefepime for
Diagnosis? ... Differential for ... systemic symptoms ... antiphospholipid syndrome ... Churg-Strauss syndrome
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Cold Agglutinin Syndrome ... , autoimmune disorder ... Clinical Presentation ... younger pts) Differential ... hemolytic #anemia #hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Myelodysplastic Syndromes ... age 70 years Symptoms ... • Anemia • Aplastic ... blood count with differential ... #diagnosis #hematology
Hair Loss (Alopecia) - General (Diffuse and Focal) Differential Diagnosis Algorithm DIFFUSE Scarring - Irreversible-biopsy required • Lupus
Diagnosis Algorithm ... • Loose anagen syndrome ... Follicularis • Aplasia ... Diagnosis #Algorithm ... #causes
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
Immunodeficiency disorder ... to 8 years Clinical ... : • Nephrotic syndrome ... (Epstein-Barr syndrome ... #diagnosis #management
Allopecia - Differential Diagnosis Framework for Hair Loss Localized / Focal Hair Loss Pattern: • Scarring Alopecia:
Diagnosis Framework ... Alopecia mucinosa, Aplasia ... , Loose anagen syndrome ... DHEAS) • ANA ... #Diagnosis #dermatology
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