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diagnosis differential rheumatology lupus sle champs criteria disorders druginduced erythematosus eularacr hypocomplementemia lymphomas lymphoproliferative management nonhodgkin pathophysiology table vasculitides vasculitis
Causes of Hypocomplementemia - CHAMPS Mnemonic C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis H - Heavy Chain deposition
Causes of Hypocomplementemia ... glomerulonephritis (>90%) S - Systemic ... Hypocomplementemia #Low ... #Complement #CHAMPS ... #differential #hematology
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus Clinical Domains: • Constitutional domain: Fever • Cutaneous domain: Non-scarring
EULAR/ACR Classification ... Criteria for Systemic ... pericarditis • Hematologic ... > 0.5 g/24 hr, Class ... anticoagulant • Complement
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
site in lymphatic system ... with lymphatic system ... are present • Classic ... Lymphoproliferative #Disorders #Classification ... pathophysiology #Hematology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
in >90% - Low ... complement - Rare ... months to years) Systemic ... complement - 50 ... druginduced #lupus #sle #comparison
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
tract, and often causes ... against MPO • Complement ... (Low levels mixed ... differential #diagnosis #rheumatology ... #classification
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