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diagnosis differential rheumatology erythematosus lupus sle vasculitis champs criteria disorders eularacr glomerulonephritis hypocomplementemia lymphomas lymphoproliferative nonhodgkin pathophysiology polycythemia progressive rapidly
Causes of Hypocomplementemia - CHAMPS Mnemonic C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis H - Heavy Chain deposition
Causes of Hypocomplementemia ... glomerulonephritis (>90%) S - Systemic ... Hypocomplementemia #Low ... #Complement #CHAMPS ... #differential #hematology
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus Clinical Domains: • Constitutional domain: Fever • Cutaneous domain: Non-scarring
EULAR/ACR Classification ... Criteria for Systemic ... pericarditis • Hematologic ... > 0.5 g/24 hr, Class ... anticoagulant • Complement
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
RPGN has three primary ... pathophysiologic causes ... staining): • Low ... differential #diagnosis #algorithm ... #rheumatology
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
site in lymphatic system ... with lymphatic system ... are present • Classic ... Lymphoproliferative #Disorders #Classification ... pathophysiology #Hematology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
anti-Smith Ab, low ... complements and ... Skin Disease Classification ... the context of primary ... , lymphopenia, low
Polycythemia - Differential Diagnosis Algorithm Polycythemia itself isn’t a diagnosis. Like many things, it is a condition
Differential Diagnosis Algorithm ... frequently affected systems ... Better call hematology ... up EPO levels Primary ... levels: realllly low
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
tract, and often causes ... against MPO • Complement ... (Low levels mixed ... differential #diagnosis #rheumatology ... #classification
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