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diagnosis differential rheumatology champs cryoglobulinemia cryoglobulins erythematosus gammopathy hypocomplementemia lupus lymphomas lymphoproliferative mgrs monoclonal nonhodgkin pathophysiology renal significance sle systemic
Causes of Hypocomplementemia - CHAMPS Mnemonic C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis H - Heavy Chain deposition
Causes of Hypocomplementemia ... - CHAMPS Mnemonic ... Hypocomplementemia #Low ... #Complement #CHAMPS ... #differential #hematology
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
hematological disorders ... factor level • Low ... serum C4 complement ... #classification ... #rheumatology #
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Lymphoproliferative Disorders ... are present • Classic ... B-Cell ~90% • Low ... #Classification ... pathophysiology #Hematology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
anti-Smith Ab, low ... complements and ... Skin Disease Classification ... Kikuchi disease • Type-I ... , lymphopenia, low
Monoclonal Gammopathy of Renal Significance (MGRS) MGRS • MGRS refers to kidney disease caused by nephrotoxic monoclonal immunoglobulins
or plasma cell disorder ... guide subtype classification ... Damages Kidneys • Low ... tubulopathy) - Complement ... vasculitis Types
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