11 results
Oral anticoagulant dosing and bridging for VTE

- Dr. Joseph Shatzel @Clotmaster 

#VTE #DOAC #Bridging #Dosing #Oral
Clotmaster #VTE #DOAC ... Anticoagulant #Anticoagulation ... Edoxaban #Loading #DVT ... #Pharmacology #Hematology
Lower Extremity Venous Thrombosis - Management and Anatomy

Deep - Superficial - Active Bleeding

#LowerExtremity #Veins #Venous #Thrombosis
Superficial - Active Bleeding ... Superficial #Deep #VTE #DVT ... #Hematology #Management ... #Anatomy #Anticoagulation
Venous Thromboembolism Treatment Algorithm
Branch points: 
Active bleeding?  Active malignancy? Provoked?

- Dr. Joseph Shatzel
@Clotmaster

#Management #VTE #DVT
points: Active bleeding ... Management #VTE #DVT ... Thromboembolism #Treatment #Hematology ... #Anticoagulation
Patient risk stratification algorithm for the treatment of cancer-associated thrombosis.

Currently, edoxaban and rivaroxaban are the only
anticoagulants (DOACs ... DVT = deep vein ... filtration rate; DOAC ... Cancer #Algorithm #Anticoagulation ... #Management #Hematology
Treatment algorithm for VTE in Malignancy

(A) Suggested treatment algorithm for symptomatic and incidental DVT or PE
and incidental DVT ... without concomitant DVT ... DOAC, direct oral ... Cancer #Algorithm #Anticoagulation ... #Management #Hematology
Perioperative Management of DOACs
Problem:
 ✖ Each year approximately 250,000 patients on chronic anticoagulation in North America
patients on chronic anticoagulation ... per treatment table ... and procedural bleeding ... with a very low bleeding ... may not require anticoagulation
(DOAC interactions) Cancer-treatment specific inducers (↑) and inhibitors (↓)
of cytochrome p450 CYP3A4 and P-glycoprotein.

DOACs are substrates
(DOAC interactions ... thereby leading ... metabolization leading ... Chemotherapy #Oncology #Hematology ... #Interactions #Table
Managing warfarin INR

Warfarin dosage must be individualized according to the patient's response to the drug, and
Over-anticoagulation ... lead to severe bleeding ... #medications #table ... decisionaid #cardiology #hematology
Longterm Venous Thromboembolism Treatment Algorithm
Treat for 3 months and reassess
 • Isolated distal DVT (without cancer)
Isolated distal DVT ... Unprovoked proximal DVT ... PE - High Bleeding ... - Not High Bleeding ... #anticoagulation
Peripartum Cardiomyopathy - Summary
1. Definition
 • Towards the end of pregnancy to 5 months postpartum
Avoid Warfarin and DOAC ... during Delivery • Stable ... Period • Breast-feeding ... suggest prophylactic anticoagulation