10 results
(DOAC interactions) Cancer-treatment specific inducers (↑) and inhibitors (↓)
of cytochrome p450 CYP3A4 and P-glycoprotein.

DOACs are substrates
) Cancer-treatment ... thereby leading ... metabolization leading ... Chemotherapy #Oncology #Hematology ... #Interactions #Table
Perioperative Management of DOACs
Problem:
 ✖ Each year approximately 250,000 patients on chronic anticoagulation in North America
Perioperative Management ... interruption per treatment ... table ... and procedural bleeding ... with a very low bleeding
Treatment algorithm for VTE in Malignancy

(A) Suggested treatment algorithm for symptomatic and incidental DVT or PE
at high risk of bleeding ... DOAC, direct oral ... #DOAC #VTE #Malignancy ... Anticoagulation #Management ... #Hematology #Oncology
Managing warfarin INR

Warfarin dosage must be individualized according to the patient's response to the drug, and
lead to severe bleeding ... #management #algorithm ... #pharmacology #treatment ... #medications #table ... decisionaid #cardiology #hematology
Esophageal Variceal Bleeding - Diagnosis and Management Summary
PRE-ENDOSCOPY
Vasoactive agents - Octreotide: 
 • 50mcg bolus →
Bleeding - Diagnosis ... and Management ... #Bleeding #Diagnosis ... #Management #treatment ... endoscopy #varices #hepatology
Preventing Decompensation in Cirrhosis 

cACLD, CSPH, and the Rule of Five
Prevention of Decompensation
Nonselective Beta Blockers (NSBB)
Preventing
Preventing recurrent variceal ... Preventing recurrent bleeding ... Cirrhosis #Prevention #treatment ... #management #hepatology
Lung Abscess - Diagnosis and Management Summary

Lung Abscess Etiology:
 • Necrosis of lung parenchyma by a
Diagnosis and Management ... • Large volume feeding ... Lung Abscess Differential ... Abscess #pulmonary #differential ... #causes #management
Peripartum Cardiomyopathy - Summary
1. Definition
 • Towards the end of pregnancy to 5 months postpartum
Differential Diagnosis ... Avoid Warfarin and DOAC ... Delivery • Stable ... Period • Breast-feeding ... #cardiology #treatment
It is important to recognize Acute Decompensated Heart Failure (ADHF) as more than just simply a
& Dry) is the treatment ... causing hypovolemia needing ... #diagnosis #differential ... #algorithm #management ... #table #foamed
Monkeypox

What?
Monkeypox virus belongs to the family Poxviridae, subfamily Chordopoxvirinae, and genus orthopoxvirus
Viral zoonotic disease that is
rectal pain, rectal bleeding ... involved DDX: Varicella ... Respiratory distress Treatment ... MPOX #Diagnosis #Management ... #Dermatology