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diagnosis treatment blood joint pain product reactions syndrome workup adult adultonset anemia antinxp2 antinxp2dm aosd aplastic arthritis behcet ckd conditions
Diagnostic Schema for Hyperferritinemia Pearl: Diseases associated with extreme elevations: 1. HLH 2. Still's disease 3. Systemic
Hyperferritinemia Pearl: Diseases ... Still's disease ... Hyperferritinemia #Algorithm ... #Differential # ... Diagnosis #Hematology
Pancytopenia - Differential Diagnosis Congenital Diseases: • GATA2 deficiency • Fanconi’s anemia • Wiskott-Aldrich syndrome • Ribosomopathy or telomeropathy Cancer: • Leukemia • Lymphoma Inflammatory
Pancytopenia - Differential ... Congenital Diseases ... • Epstein-Barr virus ... #Differential # ... Diagnosis #Hematology
Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Adult-Onset Still's ... Arthralgia/arthritis, Skin ... fraction < 20% Differential ... #management #treatment ... #rheumatology
Pancytopenia - Workup and Differential Diagnosis Algorithm Consumption Disorders 1. Autoimmune Mediated Pancytopenia 2. Splenic Sequestration Peripheral Destruction
and Differential ... Diagnosis Algorithm ... Metastatic Disease ... #Workup #Differential ... #Hematology
Pancytopenia - Workup and Differential Diagnosis Algorithm Consumption Disorders 1. Autoimmune Mediated Pancytopenia 2. Splenic Sequestration Peripheral Destruction
and Differential ... Diagnosis Algorithm ... Metastatic Disease ... #Workup #Differential ... #Hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
bone marrow + pancytopenia ... Headaches • Pale skin ... • Peripheral Pancytopenia ... Anemia #oncology #hematology ... #diagnosis #management
Adult Onset Still's Disease Systemic inflammation with urticarial rash. Rash: • Nonpruritic, evanescent (correlates with time of
Adult Onset Still's ... maculopapular skin ... #Adult #onset #Stills ... #diagnosis #rheumatology ... #management
Approach to Joint Pain - Arthritis Differential Diagnosis Framework Inflammatory Versus Noninflammatory Pain • Is it inflammatory
Pain - Arthritis Differential ... - Autoimmune Rheumatologic ... • Adult onset Still's ... #Joint #pain #Differential ... Diagnosis #MSK #rheumatology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
response to local skin ... test (this is a skin ... ) Differential Diagnosis ... Syndrome #diagnosis #management ... signs #symptoms #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Infections+++: Virus ... +, Adult-onset Still ... disease, Infection ... Lymphohistiocytosis #diagnosis #management ... treatment #summary #rheumatology
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