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diagnosis management rheumatology druginduced sle treatment comparison dermatology differential emergencies erythematosus hemeonc hemophagocytic hlh lymphohistiocytosis oncologic oncology petechiae petechial physicalexam
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
and Management Summary ... of SLE versus DIL ... • Immunologic Workup ... Positive in 60-80% of cases ... #rheumatology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
• Immunologic Workup ... Discontinuation of causal ... • Evolution: ... • Immunologic Workup ... comparison #table #rheumatology
Drug Induced Lupus (DIL) • Epidemiology: -10% of all lupus cases, drug-dependent, 4:1 to 1:1 F:M
Drug Induced Lupus ... • Immunologic Workup ... Discontinuation of causal ... • Evolution: ... #DIL #rheumatology
Causes of Petechial Rash - Differential Diagnosis Algorithm Pinpoint areas (less than 2 mm) of hemorrhage, which
Causes of Petechial ... fulminans - DIC ... Autoimmune Vasculitis (lupus ... deficiency Work ... #Causes #dermatology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Infections+++: Virus ... Drugs, Unknown cause ... inhibitors under evaluation ... management #treatment #summary ... #rheumatology
Summary of Oncologic Emergencies Neutropenic fever: - Fever + ANC < 500 → start cefepime ± vancomycin (if
Summary of Oncologic ... full infectious work-up ... syndrome): - Hematologic ... Treat underlying cause ... renal failure, pulmonary
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