11 results
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Cerebrovascular Disease ... , PRES Pathophysiology ... thrombosis and/or blood-brain ... #rheumatology # ... #management #treatment
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... Phagocytosis of blood ... Infections+++: Virus ... #management #treatment ... #summary #rheumatology
Hematuria in Post-Renal Transplant Patient
Prevalence up to 12% in the postrenal transplant patient
 • Bacterial: Escherichia
Herpes Simple Virus ... , Busulfan • Disease ... #differential #diagnosis ... #kidney #blood ... #urine #management
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
• Epstein-Barr virus ... result from low blood ... Aplastic #Anemia #oncology ... #hematology #diagnosis ... #management
Guillain-Barré Syndrome (GBS)
Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness
Epidemiology:
 • Incidence: 1
bulbar muscles DIAGNOSIS ... normal CSF white blood ... the underlying pathophysiology ... Barre #Syndrome #diagnosis ... #management #neurology
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
may precede the neurologic ... Shock, Autoimmune disease ... Etiology: • Pathophysiology ... elevated white blood ... #management #neurology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
ABO incompatible blood ... protein C and S Pathophysiology ... • Severe Liver Disease ... #Coagulation #diagnosis ... causes #treatment #management
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
monophasic Pathophysiology ... super-antigen mediated disease ... bouts of HTN Diagnostic ... MCTD - Bechet disease ... #management #neurology
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Workup: • Full Blood ... lymph node biopsy (diagnostic ... marrow biopsy - if blood ... number of sites of disease ... #oncology #management
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
Normal or low blood ... • Autoimmune disease ... Gitelman #Syndrome #diagnosis ... #nephrology #management ... #pathophysiology