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diagnosis algorithm urine causes kidney potassium rhabdomyolysis treatment alkalosis chloride defects epithelial hematuria hyponatremia hypotonic inherited low metabolic pathophysiology physiologic
Gitelman Syndrome Overview What? • Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter • Gitelman's syndrome
Gitelman Syndrome ... thiazide-sensitive sodium ... Normal or low blood ... ratio 0.5%) Differential ... #nephrology #management
Algorithm for patients with hypokalemia on the basis of the potassium-to-creatinine ratio in the urine Urine K+
patients with hypokalemia ... effective arterial blood ... , Gitelman syndrome ... urine #potassium #differential ... algorithm #diagnosis #nephrology
Hypokalemia Evaluation Algorithm Before evaluating hypokalemia, life threatening complications such as arrhythmias and paralysis should be looked
losses: • High Blood ... • Low/Normal Blood ... , Gitelman syndrome ... diagnosis #Algorithm #differential ... #potassium #nephrology
Inherited Defects in Kidney Tubule Epithelial Cells Renal glucosuria - Na+-dependent glucose cotransporter Cystinuria - Amino acid transporter Bartter
ascending limb Gitelman ... of epithelial sodium ... Defects #Kidney #Nephrology ... #Diagnosis #Differential ... #Table
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary Causes of Rhabdomyolysis: • Trauma: - Immobilization - Crush injury - Compartment
Rhabdomyolysis - Differential ... Framework and Management ... UA positive for blood ... per day until stable ... causes #treatment #nephrology
Physiologic Approach to Hypotonic Hyponatremia The next time you have a case of hypotonic hyponatremia, give the
Present (Uosm ≥100): Hypovolemia ... Cirrhosis, Nephrotic syndrome ... #Hyponatremia #differential ... #diagnosis #table ... #sodium #nephrology
Metabolic Alkalosis - Urinary Chloride Algorithm Cl- responsive metabolic alkalosis • Kidney loss of Cl-
• Normal/low blood ... , Gitelman syndrome ... the excretion of sodium ... urine #Algorithm #nephrology ... #differential #
Hematuria in Post-Renal Transplant Patient Prevalence up to 12% in the postrenal transplant patient • Bacterial: Escherichia
(Goodpasture's syndrome ... Renal #Transplant #differential ... diagnosis #kidney #blood ... #urine #management ... #treatment #nephrology
Rhabdomyolysis - Differential Diagnosis Framework Rhabdomyolysis = Destruction of skeletal muscle with leakage of contents into circulation.
B), Coxsackie virus ... Neuroleptic malignant syndrome ... Electrolytes: Hypokalemia ... Diagnosis #Causes #nephrology ... #table
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