27 results
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
SLE) - Viral infections ... Kasabach-Merritt syndrome ... Differential #Diagnosis #hematology ... #rheumatology # ... #nonpalpable #dermatology
Pancytopenia - Differential Diagnosis

Congenital Diseases:
• GATA2 deficiency
• Fanconi’s anemia
• Wiskott-Aldrich syndrome
• Ribosomopathy or telomeropathy

Cancer:
• Leukemia
• Lymphoma

Inflammatory
Wiskott-Aldrich syndrome ... deficiency Infections ... • Epstein-Barr virus ... Differential #Diagnosis #Hematology
Staphylococcal Scalded Skin Syndrome (SSSS)

A 5-year-old girl presents to the ED with a rash that started
upper respiratory infection ... Scalded #Skin #Syndrome ... SSSS #Clinical #Photo ... #Peds #Pediatrics ... #Dermatology
Herpes Zoster: Herpes virus mediated infection that occurred in this patient receiving chemotherapy 
for an underlying
Zoster: Herpes virus ... mediated infection ... vessicles in this case ... Images #Clinical #Photo ... #Dermatology #SkinRash
Causes of Thrombocytopenia - Differential Diagnosis Algorithm
 
Decreased Megakaryopoiesis
 • Aplastic Anemia
 • Toxic Damage (e.g.
Causes of Thrombocytopenia ... Non-lmmune: • HELLP Syndrome ... Vasculitis • Infection ... Diagnosis #Algorithm #Causes ... #Hematology
Genital Lesions - Differential Diagnosis Algorithm
Elevated - Vesicles:
 • Herpes simplex
Elevated - Papules / Plaques -
Human papilloma virus ... ) • Reiter's syndrome ... ) • Behcet's syndrome ... #skinlesions #dermatology ... Diagnosis #Algorithm #causes
Causes of Thrombocytosis - Differential Diagnosis
Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis):
 • Acute infection
 • Solid organ
Causes of Thrombocytosis ... Thrombocytosis): • Acute infection ... Myelodysplastic syndrome ... Differential #Diagnosis #Causes ... #hematology #secondary
Causes of Isolated Neutropenia - Differential Diagnosis Algorithm
Congenital
Medications
 • Anticonvulsants
 • Antibiotics
 • Antithyroid
 • Antihypertensive
Causes of Isolated ... Antineoplastic Viral Infection ... • Epstein-Barr Virus ... Diagnosis #Algorithm #Causes ... #Hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... ) - HELLP syndrome ... Hemolytic uremic syndrome ... Extravascular #Causes ... differential #diagnosis #hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... old, ~10,000 new cases ... risk-stratification • Risks: infection ... Myelodysplastic #Syndrome ... Management #treatment #hematology