15 results
Here is a quick guide on the common direct-acting antivirals (DAAs) for chronic hepatitis C virus
chronic hepatitis C virus ... (HCV) infection ... DAAs #Antivirals #table ... #treatment #hcv ... infectiousdisease #hepatology
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Pathophysiology ... response preceding infection ... Campylobacter jejuni - HIV ... COVID 19 - Zika virus ... Treatment: • Plasmapheresis
Causes of Isolated Neutropenia - Differential Diagnosis Algorithm
Congenital
Medications
 • Anticonvulsants
 • Antibiotics
 • Antithyroid
 • Antihypertensive
Neutropenia - Differential ... Antineoplastic Viral Infection ... • Epstein-Barr Virus ... Childhood viruses • HIV ... Algorithm #Causes #Hematology
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
fraction < 20% Differential ... Diaqnoses: • Infectious ... Coxsackie, CMV, EBV, HIV ... diagnosis #management #treatment ... #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... +++: Virus (EBV, ... Unknown cause Treatment ... diagnosis #management #treatment ... #summary #rheumatology
Guillain-Barré Syndrome (GBS)
Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness
Epidemiology:
 • Incidence: 1
Guillain-Barré Syndrome ... (HIV), and Zika ... the underlying pathophysiology ... and cauda equina TREATMENT ... SinaiBmoreIMRes #GBS #Guillain
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
: 2 hit mechanism ... : 33% • Treatment ... : No • Treatment ... Transfusion #Reactions #hematology ... diagnosis #comparison #table
Approach to Joint Pain - Arthritis Differential Diagnosis Framework

Inflammatory Versus Noninflammatory Pain
 • Is it inflammatory
Pain - Arthritis Differential ... - Autoimmune Rheumatologic ... Parvovirus B19 • HIV ... #Joint #pain #Differential ... Diagnosis #MSK #rheumatology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Idiopathic • Infections ... - HIV • Immune ... (HIV) • Parvovirus ... aplastic anemia Treatment ... Anemia #oncology #hematology
Rhabdomyolysis - Differential Diagnosis and Management Summary

Trauma:
 • Immobilization, Crush iniury, Compartment syndrome, Electrical injury
Exertional:
 •
Rhabdomyolysis - Differential ... Statins), ETOH Infection ... (Viral- HIV, Influenza ... Dermatomyositis) AKI - Pathophysiology ... per day until stable