80 results
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
→ Refer to hematology ... for workup, including ... Vasculitides, IBD, Celiac disease ... : Chronic infections ... Diagnosis #Algorithm #hematology
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
Associated with Joint Pain ... parvovirus B19 infection ... parvovirus B19 infection ... #joint #pain #skin ... differential #diagnosis #rheumatology
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison

Hodgkin's Lymphoma:
 • Epidemiology: young adults 20-30, older 50-70
 •
e.g., HIV), EBV infection ... Alcohol-induced pain ... : Pain in involved ... Etiology: - Infections ... #differential #hematology
Approach to Joint Pain - Arthritis Differential Diagnosis Framework

Inflammatory Versus Noninflammatory Pain
 • Is it inflammatory
constitutional symptoms ... - Autoimmune Rheumatologic ... Disease OLIGOARTHRITIS ... burgdorferi (Lyme disease ... Diagnosis #MSK #rheumatology
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
evaluation or workup ... for specific symptoms ... 1,500 cells/µL Workup ... drug reaction, infection ... Differential #diagnosis #hematology
Pancytopenia - Differential Diagnosis

Congenital Diseases:
• GATA2 deficiency
• Fanconi’s anemia
• Wiskott-Aldrich syndrome
• Ribosomopathy or telomeropathy

Cancer:
• Leukemia
• Lymphoma

Inflammatory
Congenital Diseases ... and Autoimmune Diseases ... deficiency Infections ... • Epstein-Barr virus ... Differential #Diagnosis #Hematology
Approach to Joint Pain

History:
Is the pain from:
	• Joint
	• Adjacent bursa
	• Tendon
	• Ligament
	• Bone
	• Muscle
	• Referred from
or nerve root Symptoms ... Calcium oxalate Infectious ... Acute or chronic infections ... #MSK #rheumatology ... #approach #workup
Functional Dyspepsia - Signs, Symptoms and Pathophysiology
Delayed gastric emptying - Postprandial fullness, nausea, vomiting
Hypersensitivity to gastric
Dyspepsia - Signs, Symptoms ... and Pathophysiology ... loss H. pylori infection ... nonerosive reflux disease ... gastroenterology #symptoms
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... +++: Virus (EBV, ... • Autoimmune diseases ... Adult-onset Still disease ... treatment #summary #rheumatology
Cold Urticaria
Prevalence - 0.05% in the population
Disease onset - Mostly 2nd to 4th decades of life
Causes
Infections 2. ... and duration of symptoms ... angioedema Other symptoms ... Nausea, abdominal pain ... Urticaria #diagnosis #rheumatology