40 results
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
Associated with Joint Pain ... parvovirus B19 infection ... parvovirus B19 infection ... Antiphospholipid-antibody syndrome ... differential #diagnosis #rheumatology
Pancytopenia - Differential Diagnosis

Congenital Diseases:
• GATA2 deficiency
• Fanconi’s anemia
• Wiskott-Aldrich syndrome
• Ribosomopathy or telomeropathy

Cancer:
• Leukemia
• Lymphoma

Inflammatory
Wiskott-Aldrich syndrome ... deficiency Infections ... • Epstein-Barr virus ... Differential #Diagnosis #Hematology
THE LIMPING OR NON-WEIGHT BEARING CHILD PATHWAY

RED FLAGS - In all cases there are specific
markers which
Malignancy - Night pain ... splenomegaly, abnormal neurology ... , back pain Haematology ... cell disease Rheumatology ... #Child #Peds #Pediatrics
Approach to Joint Pain - Arthritis Differential Diagnosis Framework

Inflammatory Versus Noninflammatory Pain
 • Is it inflammatory
By: - Chronic Infection ... burgdorferi • Virus ... - Autoimmune Rheumatologic ... • Hepatitis B virus ... Diagnosis #MSK #rheumatology
Causes of Knee Effusions - Differential Diagnosis Framework

Knee Effusion Red Flags:
1. Fever/Chills/Joint pain/Night sweats/Weight loss
	- DDX:
		-
Fever/Chills/Joint pain ... Chikungunya - Herpes virus ... Seronegative Reactive Syndrome ... Effusions: - Hematologic ... Osteochondroma Hematologic
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
lesions + Rheumatic pain ... thickening • Osteitis: pain ... causes such as infectious ... pelvis, heel, and lower ... #Rheumatology #
Causes of Fatigue - Differential Diagnosis Algorithm
Endocrine
 • Hypo/Hyperthyroidism
 • Diabetes
 • Pituitary Insufficiency
 • Adrenal
Neoplastic / Hematologic ... • Malignancy Infectious ... Epstein-Barr Virus ... Pulmonary Disease Neurologic ... Chronic Fatigue Syndrome
Extra-articular and Other Conditions Associated with Joint Pain

Eyes
  • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
Associated with Joint Pain ... Bacterial or viral infection ... - SLE Neurologic ... conditions #joint #pain ... differential #diagnosis #rheumatology
Cauda Equina Syndrome Overview

Cauda Equina Syndrome:
 • Prevalence: 1:33,000-100,000 ppl/yr
 • Incidence: 1.5-3.4 million ppl/yr
 •
Severe low back pain ... anesthesia • P - Pain ... epidural hematoma • infections ... toon • Spinal infection ... diagnosis #causes #neurology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Macrophage Activation Syndrome ... • Fever is the main ... SLE], AOSD) • Infection ... Diagnosis #Management #Hematology ... #Rheumatology