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differential hematology hemolytic causes agglutinin anemias aplastic chronic cold disease extravascular fatigue hemolysis intravascular management oncology
Autoimmune Hemolytic Anemia (AIHA) WARM AHA - Primary - Idiopathics - Secondary Infectious • Viral- HIV, EBV, HCV, HEV •
Anemia (AIHA) ... - Secondary Infectious ... EBV, HCV, HEV ... #AIHA #Diagnosis ... #Differential #Algorithm
Hemolytic Anemias - Differential Diagnosis Algorithm Signs of anemia and hemolysis: • ↓ Haptoglobin • ↑ LDH
Algorithm Signs ... Hemolysis: • Autoimmune ... (AIHAs) • Alloimmune ... Hypersplenism, Infection ... #Algorithm #hematology
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV Microcytic (MCV < 80) "TAILS": • Thalassemia
Algorithmic Approach ... - Extrinsic: Autoimmune ... Macroangiopathic, Infections ... #MCV #Algorithm ... #hematology
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
- Differential Diagnosis ... • Alloimmune ... circulation - Infections ... immune-complex hemolytic anemia ... #Hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Neutropenia - recurrent infections ... Idiopathic • Infections ... - HCV - HIV ... #oncology #hematology ... #diagnosis #management
Causes of Fatigue - Differential Diagnosis Algorithm Endocrine • Hypo/Hyperthyroidism • Diabetes • Pituitary Insufficiency • Adrenal
Hematologic • Anemia ... • Malignancy Infectious ... Epstein-Barr Virus ... Hepatitis • HIV ... Autoimmune / Inflammatory
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
women • 15% of AIHA ... , autoimmune disorder ... Mycoplasma, EBV, HIV ... CLL (older) • Autoimmune ... #hematology #diagnosis
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