12 results
hematology differential causes aplastic blood neutropenia oncology product reactions chronic clinical common cutaneous cvid diffuse disorders eschar fatigue hypogammaglobulinemia immunodeficiency
Causes of Neutropenia with Pancytopenia - Differential Diagnosis Algorithm Sequestration: • Splenomegaly Marrow Infiltration: • Hematologic and non-hematologic
- Differential Diagnosis ... Algorithm Sequestration ... malignancies • Infection ... Toxins • Aplastic Anemia ... #Hematology
Pancytopenia - Differential Diagnosis Congenital Diseases: • GATA2 deficiency • Fanconi’s anemia • Wiskott-Aldrich syndrome • Ribosomopathy or telomeropathy Cancer: • Leukemia • Lymphoma Inflammatory
Diagnosis Congenital ... deficiency • Fanconi’s anemia ... deficiency Infections ... • Epstein-Barr virus ... #Hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
bone marrow + pancytopenia ... Idiopathic • Infections ... • Peripheral Pancytopenia ... #oncology #hematology ... #diagnosis #management
Aplastic Anemia - Illness Script Signs and symptoms: • Recurrent infections from neutropenia • Mucosal bleeding from
Aplastic Anemia ... : • Recurrent infections ... Diagnosis: • Pancytopenia ... #diagnosis #management ... #treatment #hematology
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm Reactive: - Systemic Inflammatory •
- Differential Diagnosis ... Algorithm Reactive ... • CMV • HIV ... Lymphoblastic Leukemia (Pancytopenia ... #Hematology #Oncology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
- Differential Diagnosis ... procedures - Infection ... changes), high MCV anemia ... ITP, unexplained pancytopenia ... #Differential #Diagnosis
Causes of Fatigue - Differential Diagnosis Algorithm Endocrine • Hypo/Hyperthyroidism • Diabetes • Pituitary Insufficiency • Adrenal
Algorithm Endocrine ... Hematologic • Anemia ... • Malignancy Infectious ... Epstein-Barr Virus ... Hepatitis • HIV
Causes of Isolated Neutropenia - Differential Diagnosis Algorithm Congenital Medications • Anticonvulsants • Antibiotics • Antithyroid • Antihypertensive
Algorithm Congenital ... Antineoplastic Viral Infection ... • Epstein-Barr Virus ... Childhood viruses • HIV ... #Hematology
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
late adulthood • Diagnosis ... autoimmune hemolytic anemia ... and M panel Management ... Epstein-Barr syndrome, HIV ... #diagnosis #management
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
progresses to pancytopenia ... Infection - Infection ... likely to cause infections ... #Transfusion #diagnosis ... #management #hematology
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