12 results
C.diff - Clostridioides Difficile Infection (CDI) - Diagnosis and Management - GrepMed Handbook

Clinical Presentation + Progression:
Perforation) Pathophysiology ... Tx Management (IDSA ... IDSA 2021 CDI ... Treatment Guideline ... #infectiousdiseases
CNS Infection in HIV / AIDS - Differential Diagnosis Framework

Principles of HIV-Associated CNS Opportunistic Infections:
 •
Antimicrobial treatment ... status, and focal neurologic ... confusion, and focal neurologic ... opportunistic #InfectiousDiseases ... #Neurology
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... →Activation of CD8 ... Infections+++: Virus ... Unknown cause Treatment ... diagnosis #management #treatment
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Guillain-Barre Pathophysiology ... COVID 19 - Zika virus ... Treatment: • Plasmapheresis ... diagnosis #management #treatment ... #neurology
HIV-Associated Neurocognitive Disorder (HAND)

Definition:
HIV-Associated Neurocognitive disorders categories:
• Asymptomatic neurocognitive impairment
• Mild neurocognitive impairment
• HIV dementia

Pathophysiology:
HIV frequently
HIV dementia Pathophysiology ... HIV and with low CD4 ... Treatment: • HAART ... treatment • Cognitive ... dementia #AIDS #Neurology
Guillain-Barré Syndrome (GBS)
Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness
Epidemiology:
 • Incidence: 1
, Epstein-Barr virus ... HIV), and Zika virus ... the underlying pathophysiology ... and cauda equina TREATMENT ... diagnosis #management #neurology
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
monophasic Pathophysiology ... zoster, West Nile virus ... Herpes simplex virus ... Transverse Myelitis Treatment ... diagnosis #management #neurology
Mycoses

HISTOPLASMOSIS
• Inhalation of conidia → Yeast → travel to lymph nodes → spread in body
• Bird
Histoplasmosis Treatment ... by culture or serology ... Aspergillosis Pathophysiology ... Diagnosis: • Serology ... ) #Mycoses #InfectiousDiseases
"Scrotal Pain + Uganda:Almost never see it in the developed world unless you are like this
to call up the CDC ... some experimental treatment ... Clinical #POCUS #Urology ... #InfectiousDiseases
IDSA Recommendations for Preventing and Treating Varicella Zoster Virus (VZV) Infections in HIV-AIDS
Pre-Exposure Prevention of VZV
IDSA Recommendations ... Varicella Zoster Virus ... patients with CD4 ... , treatment with ... #Zoster #VZV #IDSA