13 results
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Diagnosis: >3 symptoms ... initiation • Differential ... Diagnosis: Infection ... sepsis), PE, DAH, CHF ... #diagnosis #management
CNS Infection in HIV / AIDS - Differential Diagnosis Framework

Principles of HIV-Associated CNS Opportunistic Infections:
 •
HIV / AIDS - Differential ... pathogens, including PML ... Antimicrobial treatment ... Hydrocephalus possible PML ... #differential #
Guillain-Barré Syndrome (GBS)
Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness
Epidemiology:
 • Incidence: 1
to a preceding infection ... • Most common infection ... than one after symptom ... and cauda equina TREATMENT ... Syndrome #diagnosis #management
HIV-Associated Neurocognitive Disorder (HAND)

Definition:
HIV-Associated Neurocognitive disorders categories:
• Asymptomatic neurocognitive impairment
• Mild neurocognitive impairment
• HIV dementia

Pathophysiology:
HIV frequently
early stages of infection ... • Depressive symptoms ... (JC virus) Brain ... : • Increased CSF ... Treatment: • HAART
Rheumatoid Arthritis Summary
Overview: chronic, inflammatory symmetric polyarthritis involving small joints of hands/feet, knees, shoulders
Signs & Symptoms:
of hands/feet, knees ... shoulders Signs & Symptoms ... exam and imaging Treatment ... Arthritis #diagnosis #management ... #rheumatology
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS

What Is IRIS?
	• A state of hyperinflammatory response that
leukoencephalopathy (PML ... Confusion, visual symptoms ... Leishmaniasis Differential ... Inflammatory #Syndrome #Differential ... #Diagnosis #Management
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
Bilateral signs and/or symptoms ... Herpes simplex virus ... Transverse Myelitis Treatment ... Myelitis #diagnosis #management ... #neurology #differential
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Neutropenia - recurrent infections ... Idiopathic • Infections ... aplastic anemia Treatment ... • Improve the symptoms ... #diagnosis #management
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
Neurological symptoms ... Reversible course Differential ... Diagnosis: • Infection ... epilepticus Treatment ... Syndrome #diagnosis #management
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
very remarkable w/differential ... vasculitis vs infection ... Treatment of GCA ... them, but urgent rheumatology ... #Diagnosis #Management